Branch retinal vein occlusion following ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccine

Abstract

Purpose To present a case of branch retinal vein occlusion (BRVO) following ChAdOx1 nCoV-19 (Oxford-AstraZeneca) Vaccine. Methods Case report. Results A 60-year old otherwise healthy Caucasian male, presented to the ophthalmology emergency clinic complaining of sudden, painless vision loss in his right eye of 24 h” duration. The patient had received Vaxveria seven days prior. The clinical and fundus examination of the right eye established the diagnosis of BRVO. Conclusion The present case descibes the occurrence of BRVO soon after the vaccination with the Oxford-AstraZeneca vaccine. The close temporal relationship between the BRVO incidence and the vaccination is reinforced by the lack of othe subjective cause to justify the episode.

COVID-19, post-acute COVID-19 syndrome (PACS, “long COVID”) and post-COVID-19 vaccination syndrome (PCVS, “post-COVIDvac-syndrome”): Similarities and differences

“…In case of COVID-19 vaccination, vaccine-induced immune thrombotic thrombocytopenia (VITT), which can lead to cerebral venous sinus thrombosis, has been found to be particularly associated with the adenovirus vector-based COVID-19 vaccines [234] , [235] , [236] , [237] , [238] , [239] , [240] , [241] , [242] . Another example are retinal artery/vein occlusions induced by SARS-CoV-2 infection [243] , [244] , [245] , [246] , [247] , [248] , [249] , [250] , [251] , [252] , [253] , [254] , [255] , [256] , [257] , [258] , [259] , [260] , [261] , [262] and COVID-19 vaccination [263] , [264] , [265] , [266] , [267] , [268] , [269] , [270] , [271] , [272] , [273] , [274] , [275] , [276] , [277] , [278] , [279] , [280] , [281] , [282] , [283] , [284] , [285] , [286] , [287] , [288] , [289] , [290] , [291] , [292] , which can thus can be considered part of the symptoms of COVID-19 and PCVS. Noteworthy, induced retinal artery/vein occlusions induced COVID-19 vaccination were found to be “more common than anticipated” [263] .…”

Retinal Vein Occlusion Amongst People Vaccinated by mRNA- and Viral Vector- COVID-19 Vaccines: A Systematic Review

“…Those conditions were known as Virchow’s triad and it applied to some diseases like deep vein thrombosis (DVT). 17 , 33 , 57 It was suggested to share the risk factor with RVO, such as cardiovascular and systemic risk factors, like hypertension, hyperlipidemia, diabetes mellitus, hematological disorders, glaucoma/ocular hypertension, or familial RVO. 17 …”

Possible association between vaccination against SARS-CoV-2 and recurrence of macular edema due to branch retinal vein occlusion: a case report

“…Several ocular adverse events related to these vaccines have been reported. 3,5–14 For example, several reports described the occurrence of retinal vein occlusion (RVO) after vaccination. 3,6–14 Vujosevic et al.…”

“…3,5–14 For example, several reports described the occurrence of retinal vein occlusion (RVO) after vaccination. 3,6–14 Vujosevic et al. 10 stated that RVO can be considered a rare ophthalmic complication after vaccination against SARS-CoV-2.…”

“…4 Several ocular adverse events related to these vaccines have been reported. 3,[5][6][7][8][9][10][11][12][13][14] For example, several reports described the occurrence of retinal vein occlusion (RVO) after vaccination. 3,[6][7][8][9][10][11][12][13][14] Vujosevic et al 10 stated that RVO can be considered a rare ophthalmic complication after vaccination against SARS-CoV-2.…”