Branch Retinal Arterial Occlusions in Multifocal Retinitis With Optic Nerve Edema

Cohen, Steven M.; Davis, Janet L.; Gass, J. Donald M.

doi:10.1001/archopht.1995.01100100059029

Cited by 51 publications

(26 citation statements)

References 21 publications

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“…[3][4][5] Disseminated CSD may involve the eye and cause vision-threatening manifestations, including neuroretinitis, optic neuritis, retinitis, choroiditis, anterior uveitis, vitritis, branch retinal arteriolar and venular occlusions, vasculitis, and peripapillary angiomatosis. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] In 1970, Sweeney and Drance 22 were first to find a connection between CSD and the appearance of neuroretinitis. Since then, numerous reports had been published on cases of neuroretinitis in CSD and it is the most common posterior segment complication of CSD.…”

Section: Introductionmentioning

confidence: 99%

Macular findings on optical coherence tomography in cat-scratch disease neuroretinitis

Habot‐Wilner

Zur

Goldstein

et al. 2011

Eye

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Purpose To describe the macular findings on optical coherence tomography (OCT) in patients with cat-scratch disease (CSD) neuroretinitis. Methods Medical records of all patients diagnosed with CSD neuroretinitis at the Tel Aviv Medical Center between April 2006 and May 2010 were retrospectively reviewed. All patients underwent Stratus OCT macular examination. Results Eight eyes of seven patients with confirmed CSD neuroretinitis, (mean age 33±9.9 years, range 6-48 years) were included in the study. All patients presented clinically with optic nerve swelling and macular edema or macular exudates. OCT demonstrated flattening of the foveal contour, thickening of the neurosensory retina, and accumulation of subretinal fluid (SRF) in all studied eyes. Retinal exudates appeared as multiple hyper-reflective foci in the outer plexiform layer. The average central macular thickness was 460 lm (range 170-906 lm) and the average maximal retinal thickness was 613 lm (range 387-1103 lm), at presentation. The macula appeared normal on repeated exams during follow-up. Conclusion Similar OCT findings were demonstrated in patients with CSD neuroretinitis. SRF was found in all eyes, although was not visible on clinical examination or fluorescein angiography. OCT may be used as an adjunct imaging tool in the diagnosis and follow-up of patients with CSD neuroretinitis.

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Section: Introductionmentioning

confidence: 99%

Macular findings on optical coherence tomography in cat-scratch disease neuroretinitis

Habot‐Wilner

Zur

Goldstein

et al. 2011

Eye

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“…16 In recent case reports, cat scratch disease was also related to neuroretinitis with retinal lesions, multifocal choroiditis with multiple arterial branch occlusions, serous macular detachment, and intermediate uveitis. [17][18][19][20][21] Patients and methods Nine patients with neuroretinitis and four with panuveitis and positive antibody titres for B henselae were seen in the FC Donders Institute, University Hospital Utrecht, between January 1995 and February 1997. All patients underwent a standard diagnostic screening procedure, which consisted of erythrocyte sedimentation rate (ESR), red and white blood cell counts, serum angiotensin converting enzyme levels, syphilis, borrelia and toxoplasma serology, and chest radiography.…”

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confidence: 99%

Presumed Ocular Bartonellosis

Kerkhoff¹,

Ossewaarde²,

Ws³

et al. 1999

Journal of Neuro-Ophthalmology

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Background-The spectrum of diseases caused by Bartonella henselae continues to expand and ocular involvement during this infection is being diagnosed with increasing frequency. Methods-The clinical features and visual prognosis for 13 patients with intraocular inflammatory disease and laboratory evidence of bartonellosis were investigated. There were nine patients with neuroretinitis and four with panuveitis with positive antibody titres against B henselae determined by an enzyme immunoassay (IgG exceding 1:900 and/or IgM exceeding 1:250). Results-Positive IgG levels were found for eight patients and positive IgM levels for five. Despite animal exposure of 10 patients, only two (IgG positive) cases had systemic symptoms consistent with the diagnosis of cat scratch disease. Pathological fluorescein leakage of the optic disc was observed in all aVected eyes. At 6 months' follow up, 3/18 (17%) aVected eyes had a visual acuity of less than 20/100, owing to optic disc atrophy and cystoid macular oedema. 12 patients (17 eyes) were treated with antibiotics; visual acuity improved two or more Snellen lines for 9/17 (53%) eyes. Conclusions-The possibility of B henselae infection should be considered in patients with neuroretinitis and panuveitis (especially in cases with associated optic nerve involvement) even in the absence of systemic symptoms typical for cat scratch disease. (Br J Ophthalmol 1999;83:270-275)

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“…peripapillary angiomatosis, 8 retinal and optic nerve head neovascularization, 9 and retinal artery occlusion. 10 The arm-to-retina circulation time in the present patient was significantly elongated to 37 seconds, suggesting that the prelaminar artery system had heavy resistance to inflow, probably because of Bartonella organism itself or decreased internal diameter of the artery following inflammation of vascular endothelium cells. As a result, the stagnation of blood flow and the obliteration in the optic disc circulation system may develop into an ischaemic state to affect the optic nerve fibres.…”

Section: Discussionmentioning

confidence: 55%

Bilateral Neuroretinitis in Cat Scratch Disease with Exudative, Obliterative Vasculitis in the Optic Disc

Tagawa

Suzuki

Sakaguchi

et al. 2014

Neuro-Ophthalmology

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A 29-year-old fisherman exhibited optic disc oedema and peripapillary retinal detachment in the right eye, whereas in the left eye, optic atrophy and intraretinal exudates were already observed on first examination. About 6 months earlier, he noticed blurred vision of the left eye but took no medication. Visual acuity was 0.4 OD and 0.01 OS. Perimetry showed a large lower-half field defect with sparing 10 central field in the right eye and a large central scotoma in the left eye. Fluorescein angiography showed existence of arteriole or capillary nonperfusion and hyperpermeability of surrounding capillaries. Since serological examinations showed positive Bartonella immunoglobulin G (IgG) and other causes of neuroretinitis (NR) were excluded, NR in the present case was caused by cat scratch disease (CSD). Optic atrophy appeared 2 weeks after onset. Optical coherence tomography 13 weeks after onset revealed severe loss of retinal nerve fibre layer (RNFL) superior and nasal to the optic disc in both eyes and temporal in the left eye. Visual acuity of the right eye improved to 1.2 by the treatment, whereas visual field defects were persistent. CSD-NR in the present case developed abrupt appearance of optic atrophy with severe RNFL loss in the right eye, which was elicited by exudative, obliterative vasculitis in the superficial layer of the optic disc.

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Branch Retinal Arterial Occlusions in Multifocal Retinitis With Optic Nerve Edema

Cited by 51 publications

References 21 publications

Macular findings on optical coherence tomography in cat-scratch disease neuroretinitis

Macular findings on optical coherence tomography in cat-scratch disease neuroretinitis

Presumed Ocular Bartonellosis

Bilateral Neuroretinitis in Cat Scratch Disease with Exudative, Obliterative Vasculitis in the Optic Disc

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