Brain Volume Fractions in Mammals in Relation to Behavior in Carnivores, Primates, Ungulates, and Rodents

Abstract

The volume fraction (VF) of a given brain region, or the proper mass, ought to reflect the importance of that region in the life of a given species. This study sought to examine the VF of various brain regions across 61 different species of mammals to discern if there were regularities or differences among mammalian orders. We examined the brains of carnivores (n = 17), ungulates (n = 8), rodents (n = 7), primates (n = 11), and other mammals (n = 18) from the online collections at the National Museum of Health and Medicine. We measured and obtained the VF of several brain regions: the striatum, thalamus, neocortex, cerebellum, hippocampus, and piriform area. We refined our analyses by using phylogenetic size correction, yielding the corrected (c)VF. Our groups showed marked differences in gross brain architecture. Primates and carnivores were divergent in some measures, particularly the cVF of the striatum, even though their overall brain size range was roughly the same. Rodents predictably had relatively large cVFs of subcortical structures due to the fact that their neocortical cVF was smaller, particularly when compared to primates. Not so predictably, rodents had the largest cerebellar cVF, and there were marked discrepancies in cerebellar data across groups. Ungulates had a larger piriform area than primates, perhaps due to their olfactory processing abilities. We provide interpretations of our results in the light of the comparative behavioral and neuroanatomical literature.

Clade-specific forebrain cytoarchitectures of the extinct Tasmanian tiger

“…We quantified the overall volume of the cerebellum and found that it scales with brain volume when compared to other mammals ( Fig. 7 D ), further demonstrating that the thylacine brain shows highly conserved trends with other species ( 36 , 47 ).…”

“…The scaling of brain region volumes was analyzed and compared with data from metatherian and eutherian brains studied using equivalent metrics ( 13 , 35 , 36 , 43 , 47 , 55 ). Taxonomic data were collected for each species via the taxize package in R ( 56 ).…”