Brain Tissue Water Uptake after Middle Cerebral Artery Occlusion Assessed with CT

Dzialowski, Imanuel; Weber, Johannes; Doerfler, Arnd; Forsting, Michael; Kummer, Rüdiger von

doi:10.1177/1051228403258135

Cited by 38 publications

(14 citation statements)

References 23 publications

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“…Usually, the ADC drops more than 20% but on CT, the EIE induces a decrease of Hounsfield units of about 0.1% only (referring to the zero point of both scales). Our results indicated a 1.5-HU decrease per percent water increase [25], with good correspondence to animal experiments [120]. EIS on CT are regularly smaller than the corresponding ADC lesion and Somford et al [121] could also prove, that more severe ADC decrease was present in regions with EIS on CT.…”

Section: Dwi Sensitively Detects An Early Stage Of the Early Ischemicsupporting

confidence: 63%

“…It is noticeable as subtle hypodense changes on CT scans after approximately 45 min in patients [26] -compared to observation of clear diffusion impairment after only 11 min [119]. CT density decrease is directly correlated with water increase [120] and thus represents a tool to monitor the EIE in patients. In contrast to the time course of ADC, CT density decrease is detected later but declines linearly within the first hours [25] thus representing a tissue clock of ischemic tissue damage.…”

Section: Dwi Sensitively Detects An Early Stage Of the Early Ischemicmentioning

confidence: 99%

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Imaging in Acute Stroke – a Personal View*

Kucinski

2009

Clin Neuroradiol

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Acute stroke imaging has developed from intraarterial angiography and native, unenhanced CT to highly elaborated tools with the access to a variety of pathophysiological variables ahead of therapy. Despite enduring unresolved problems, we can now obtain a comprehensive view on the individual patient's disease and act fast and specifically under consideration of chances and risks of different therapies. The stroke neuroradiologist is the decisive partner of engaged clinical disciplines and should own a leading role in future acute stroke trials. Weighing the different modalities against each other, there is an established advantage of acute stroke MRI over CT based on diffusion-weighted imaging and the possibility to obtain even more functional information on stroke pathophysiology.

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Section: Dwi Sensitively Detects An Early Stage Of the Early Ischemicsupporting

confidence: 63%

Section: Dwi Sensitively Detects An Early Stage Of the Early Ischemicmentioning

confidence: 99%

Imaging in Acute Stroke – a Personal View*

Kucinski

2009

Clin Neuroradiol

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“…CT is highly specific for the early identification of ischaemic brain damage [132, 140, 141]. The presence of early signs of ischaemia on CT should not exclude patients from thrombolysis within the first 3 h, though patients with a hypoattenuating ischaemic lesion which exceeds one third of the middle cerebral artery (MCA) territory may benefit less from thrombolysis [126, 134, 135, 142, 143].…”

Section: Diagnosticsmentioning

confidence: 99%

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008

Ringleb¹,

Bousser²,

Ford³

et al. 2008

Cerebrovasc Dis

2,105

567

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This article represents the update of the European Stroke Initiative Recommendations for Stroke Management. These guidelines cover both ischaemic stroke and transient ischaemic attacks, which are now considered to be a single entity. The article covers referral and emergency management, Stroke Unit service, diagnostics, primary and secondary prevention, general stroke treatment, specific treatment including acute management, management of complications, and rehabilitation.

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“…Нативную КТ головного мозга осуществляли в 1-е и 5-е сутки (у 11 человек) посттравматического периода. КТ-перфузию [5] проводили только при поступлении, для нее использовали контрастный препарат ультравист кон-центрацией 300-370 мг/мл объемом 50 мл, который вво-дили болюсно со скоростью 4 мл/с. Выбирали переднюю мозговую артерию, вену Галена, прямой синус либо сток синусов.…”

Section: материал и методыunclassified

Perfusion computed tomography in the diagnosis of mild brain injury

Balandina¹,

Шевченко²,

Zolotovskaya³

2016

Z. nevrol. psikhiatr. im. S.S. Korsakova

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КратКОе сООбщениеВажным звеном патогенеза черепно-мозговой трав-мы (ЧМТ) является нарушение мозгового кровообраще-ния [1]. Однако в литературе [2-4] преимущественно ос-вещена ЧМТ с множественными переломами костей че-репа и выраженной деструкцией головного мозга, при которой гемодинамические нарушения значительны и во многом определяют течение и исход заболевания. Иссле-дования же, касающиеся цереброваскулярных рас-стройств при легкой ЧМТ, когда нарушения не столь дра-матичны, носят фрагментарный характер.Цель исследования -по данным перфузионной ком-пьютерной томографии (КТ) оценить и сопоставить осо- Цель исследования. По данным перфузионной компьютерной томографии (КТ) оценить и сопоставить особенности регионального мозгового кровотока пациентов с сотрясением и ушибом головного мозга легкой степени. материал и методы. обследованы 38 мужчин в возрасте 18-35 лет в остром периоде легкой черепно-мозговой травмы (ЧМТ): 21 -с сотрясением головного мозга, 17 -с ушибом головного мозга легкой степени тяжести. Группу контроля составили 7 мужчин аналогичного возраста без ЧМТ. результаты и заключение. данные КТ-перфузии показали, что в обеих группах определялись сдвиги показателей гемодинамики генерализованного характера. установлено статистически значимое увеличение показателей среднего времени и снижение общего объема прохождения крови через выбранные участки. у всех пострадавших в остром периоде легкой ЧМТ выявлялась гипоперфузия, обусловленная в первую очередь генерализованным вазоспазмом. При ушибе головного мозга легкой степени тяжести в отличие от сотрясения мозга при КТ-перфузии определялись очаговые нарушения мозгового кровообращения, локализующиеся в полюсах лобных и височных долей. Использование КТ-перфузии поможет улучшить диагностику легкой ЧМТ. Objective. To evaluate and compare the characteristics of the regional cerebral blood flow in patients with mild cerebral concussion or injury using the results of perfusion computed tomography (CT). Material and methods. Thirty-eight men, aged 18-35 years, including 21 with concussion and 17 with mild cranial/brain injury (CBI), were examined at the early stage of disease. The control group consisted of 7 age-matched men with non-confirmed CBI. Results and conclusion. The results of CT-perfusion revealed generalized changes in the hemodynamics. There was a significant increase in the mean time and decrease in the total volume of blood flow through selected regions. hypoperfusion caused by generalized vasospasm was found in all patients at the early stage of mild CBI. Focal disturbances of cerebral blood flow localized in the poles of the frontal and temporal lobes were determined in patients with mild brain injury compared to the patients with concussion. The use of CT-perfusion can improve the diagnosis of mild CBI.

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Brain Tissue Water Uptake after Middle Cerebral Artery Occlusion Assessed with CT

Abstract: After MCA occlusion, immediate brain tissue net water uptake is associated with a decrease in x-ray attenuation. CT can monitor ischemic edema in an acute stroke.

Cited by 38 publications

References 23 publications

Imaging in Acute Stroke – a Personal View*

Imaging in Acute Stroke – a Personal View*

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008

Perfusion computed tomography in the diagnosis of mild brain injury

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