Brain structural changes in alternating hemiplegia of childhood using single‐case voxel‐based morphometry analysis
Elly Arizono,
Noriko Sato,
Yoko Shigemoto
et al.
Abstract:Background and purposeAlternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disease caused by ATP1A3 mutations. Using voxel‐based morphometry (VBM) analysis, we compared an AHC patient cohort with controls. Additionally, with single‐case VBM analysis, we assessed the associations between clinical severity and brain volume in patients with AHC.Materials and methodsTo investigate structural brain changes in gray matter (GM) and white matter (WM) volumes between 9 patients with AHC and 20 age‐mat… Show more
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