Abstract:BACKGROUND: Whole brain radiation therapy (WBRT) is an effective palliative measure and provides durable symptom relief in lung cancer patients with multiple brain metastases (BM). Clinico radiological progression of BM after WBRT is a common and challenging scenario; treatment is tailored, with various factors like driver mutation status, age, performance status, progression free interval and time since last irradiation influencing the treatment decision. Surgery or focal RT with stereotactic techniques may b… Show more
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