Brain Networks for Cortical Atrophy and Responsive Neurostimulation in Temporal Lobe Epilepsy
Sara Larivière,
Frédéric L. W. V. J. Schaper,
Jessica Royer
et al.
Abstract:ImportanceDrug-resistant temporal lobe epilepsy (TLE) has been associated with hippocampal pathology. Most surgical treatment strategies, including resection and responsive neurostimulation (RNS), focus on this disease epicenter; however, imaging alterations distant from the hippocampus, as well as emerging data from responsive neurostimulation trials, suggest conceptualizing TLE as a network disorder.ObjectiveTo assess whether brain networks connected to areas of atrophy in the hippocampus align with the topo… Show more
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