Brain Imaging in Cases with Positive Serology for Dengue with Neurologic Symptoms: A Clinicoradiologic Correlation

Vanjare, Harshad Arvind; Mannam, Pavithra; Mishra, Ajay Kumar; Karuppusami, Reka; Carey, Ronald Albert Benton; Abraham, Asha Mary; Rose, Winsley; Iyyadurai, Ramya; Mani, Shailendra

doi:10.3174/ajnr.a5544

Cited by 20 publications

(21 citation statements)

References 26 publications

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“…Another report described changes mimicking multiple sclerosis at MRI in their patients, positive for dengue. 59 We have seen, in our 5 16…”

Section: Encephalopathy Versus Encephalitismentioning

confidence: 81%

“…However, in prone individuals, severe dengue (dengue hemorrhagic fever or dengue shock syndrome) may ensue, potentially leading to inevitable death. Dengue infection uncommonly presents with neurological symptoms; this can be seen in 4–5% of those infected . Encephalopathy, if present, is presumed to occur due to the multisystem derangement in severe dengue.…”

Section: Pathophysiologymentioning

confidence: 99%

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Neuroimaging in dengue:CTandMRIfeatures

Noh

Rashid

Zaidi

et al. 2018

Neurology & Clinical Neurosc

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Neurological manifestations of dengue are increasingly seen, especially in endemic regions. The wide availability of cross sectional imaging has allowed radiological depiction of CNS involvement in symptomatic patients. Classically, dengue was thought to be a nonneurotropic virus; however, increasing evidence is suggesting central nervous system involvement. A number of pathophysiologic mechanisms have been proposed to explain the development of the neurological symptoms seen. Although there is no specific neuroimaging feature at present, knowledge of its variable appearance may aid in treatment, prognostication, and follow up. In this article, we attempt to review, comprehensively, the spectrum of neuroimaging findings in dengue, via CT and MRI. We also discuss some common pitfalls associated with this disease entity.

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“…Another report described changes mimicking multiple sclerosis at MRI in their patients, positive for dengue. 59 We have seen, in our 5 16…”

Section: Encephalopathy Versus Encephalitismentioning

confidence: 81%

Section: Pathophysiologymentioning

confidence: 99%

Neuroimaging in dengue:CTandMRIfeatures

Noh

Rashid

Zaidi

et al. 2018

Neurology & Clinical Neurosc

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“…Sie hat sich zunehmend geografisch ausgedehnt und ist in den letzten 50 Jahren in zahlreichen Ländern neu aufgetreten, überwiegend in den tropischen Regionen der beiden Amerikas, in Südostasien und im westlichen Pazifikraum [27,29]. Die internationale Ausbreitung des Dengue-Virus lässt sich durch mehrere Faktoren erklären.…”

Section: Merkeunclassified

“…Allerdings eignet sich die MRT für die Darstellung des klassischen Musters einer Dengue-Virus-Enzephalitis besser als die CT. Dieses Muster besteht in T2w hyperintensen Herden, die die kortikale graue Substanz, die subkortikale und tiefe weiße Substanz, die Basalgan- glien und die Thalami betreffen. Für gewöhnlich weisen sie einen gewissen expansiven Effekt auf [26,29]. Bei den meisten Patienten sind unregelmäßige Areale mit einer Diffusionsrestriktion in den betroffenen Bereichen zu erkennen, ebenso wie Mikrohämorrhagien, die in der suszeptibilitätsgewichteten MRT als kleine Foki mit Blooming-Effekt imponieren [26,29].…”

Section: Bildgebungunclassified

Neurologische Bildgebung bei neu oder wieder vermehrt auftretenden Infektionen

Carmo¹,

Simão²,

Amaral³

et al. 2020

Neuroradiologie Scan

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Infectious diseases emerge and reemerge over the years, and many of them can cause neurologic disease. Several factors contribute to the emergence and reemergence of these conditions, including human population growth, an increase in international travel, the geographic expansion of recognized pathogens to areas where they were previously nonendemic, and greater contact with wild animal reservoirs. The antivaccination social movement has played an important role in the reemergence of infectious diseases, especially some viral conditions. The authors review different viral (arboviruses such as dengue, chikungunya, and Zika virus; enterovirus 71; measles; and influenza), bacterial (syphilis, Lyme disease, and listeriosis), and parasitic (Chagas disease) diseases, focusing primarily on their neurologic complications. Although there are several additional infectious diseases with central nervous system manifestations that could be classified as emergent or reemergent, those listed here are the most relevant from an epidemiologic standpoint and are representative of important public health issues on all continents. The infections caused by these pathogens often show a variety of neuroimaging patterns that can be identified at CT and MRI, and radiology is central to the diagnosis and follow-up of such conditions. Given the increasing relevance of emerging and reemerging infections in clinical practice and public health scenarios, radiologists should be familiar with these infections.

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“…W e thank Dr Pathum Sookaromdee and Professor Viroj Wiwanitkit for their interest in our recent publication. 1 The authors have stated that the brain imaging findings in cases with dengue infection are nonspecific and are of little help in diagnosis, management, or prognostication.…”

Section: Replymentioning

confidence: 99%