Brain health: The hidden casualty of a humanitarian crisis

Marshall, Charles R.; Noyce, Alastair; Neligan, Aidan; Dobson, Ruth

doi:10.1016/j.lanepe.2022.100374

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…Arguably, additional FM and depression-specific treatments are warranted in all patients with RA with significant FM. 28 Recent clinical studies on medical conditions from during the Ukraine war and the Haiti Earthquake of 2010 35 36 highlight the importance of studying chronic diseases during exceptional times, much like our study own study from the COVID-19 pandemic. Individually, the outcomes of our RA cohort at 1 year and beyond would likely be suboptimal, even if we were to employ T2T strategies longitudinally, solely because of the additional impact of FM, depression and anxiety, which was also seen in other studies.…”

Section: Discussionmentioning

confidence: 68%

Fibromyalgia and mental health in rheumatoid arthritis: a cross-sectional prevalence study from the COVID-19 pandemic

Upadhyaya,

Malgutte,

Handa

et al. 2023

BMJ Open

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ObjectivesThis study evaluated the prevalence of fibromyalgia (FM), anxiety and depression in patients with rheumatoid arthritis (RA) and their effects on the clinical parameters of RA during the COVID-19 pandemic.DesignCross-sectional, outpatient clinic, observational, non-interventional.SettingSingle-centre, tertiary care, multispecialty, service and research hospital, north-central India.ParticipantsAdult patients with RA, controls.ResultsThis cross-sectional study included 200 patients with RA diagnosed with the American College of Rheumatology/European League Against Rheumatism 2010 (ACR) criteria and 200 controls. FM was diagnosed using the revised 2016 ACR FM Criteria. Disease activity, quality of life and functional disability in patients with RA were assessed using multiple Disease Activity Scores. The presence of depression and anxiety was determined using the Hospital Anxiety and Depression Scale. FM was present in 31% of patients with RA compared with 4% of controls in our study. Patients with RA with FM were older, predominantly females with longer disease duration, and more likely to be on steroids. Patients with RA with FM had a higher disease activity, and none of our RA with FM patients were in remission. The multivariable analysis found FM to be an independent predictor of the Simplified Disease Activity Index for RA. Patients with RA with FM had worse functional ability and poorer quality of life. The prevalence of anxiety and depression was 12.5% and 30%, significantly higher in RA with FM patients.ConclusionDuring the COVID-19 pandemic, around one-third of our study patients had FM and depression, significantly higher than pre-COVID-19 times. Thus, mental health assessment should be incorporated into the routine management of patients with RA.

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Section: Discussionmentioning

confidence: 68%

Fibromyalgia and mental health in rheumatoid arthritis: a cross-sectional prevalence study from the COVID-19 pandemic

Upadhyaya,

Malgutte,

Handa

et al. 2023

BMJ Open

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“…Another major impact of these crises must be on the overall health status of the Ukrainians, expressed in indices like life expectancy, crude mortality or child mortality, as well as on the incidence of specific diseases due to a worsened prevention (e.g., tuberculosis or cancer). The situation must also impact mental health, a specific domain which should be carefully monitored [1], including the cases of post-traumatic syndrome [2]. Finally, there must also be an impact on the health care system which is under severe pressure [3] due to the destruction of health care facilities in Ukraine, the afflux of traumas and injuries, and the exodus of health care professionals from this state.…”

Section: Impacts Of War In Ukrainementioning

confidence: 99%

Perspective of schools of public health on war in Ukraine – reactions to military conflict in Europe and international cooperation

Bochenek

Chambaud

Lozan

2022

Zdrowie Publiczne I Zarządzanie

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Since February 24, 2022, the hybrid war between Russia and Ukraine has been transformed into a very severe and open military conflict, having dramatic humanitarian and public health consequences – first of all, for the Ukrainians, but also for the whole world, in various dimensions. The impacts of this war are complex, multidimensional and multilateral. This paper aims to characterize the selected major impacts of the ongoing war on public health, as well as to characterize the selected reactions of the international academic public health community, including especially the three organizations from Moldova, Poland and France. Several positive responses of the academic community to the unprecedented humanitarian and public health crises caused by the Russo-Ukrainian war have been described. These efforts should be continued, developed and modified to the dynamically changing situation. The already existing international cooperation platforms, networks and alliances should be used for that purpose.

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“…Despite the growing recognition of the importance of social determinants of health, little progress has been made towards addressing these determinants in people living with MS. Emerging data suggest that the cumulative effects of exposure to social and environmental stressors can manifest in later adulthood and have a negative effect on general and brain health 4 . A holistic approach that includes consideration of social determinants of health, which can be considered the 'risks of risks', offers the potential for opportunities to fundamentally improve health and health care in MS and other neurological diseases.…”

Section: Introductionmentioning

confidence: 99%

Social determinants of health in multiple sclerosis

et al. 2022

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Social determinants of health are the conditions in which people are born, grow, live, work and age. These circumstances are the nonmedical factors that influence health outcomes. Evidence indicates that health behaviours, comorbidities and disease-modifying therapies all contribute to multiple sclerosis (MS) outcomes; however, our knowledge of the effects of social determinants -that is, the 'risks of risks' -on health has not yet changed our approach to MS. Assessing and addressing social determinants of health could fundamentally improve health and health care in MS; this approach has already been successful in improving outcomes in other chronic diseases. In this narrative Review, we identify and discuss the body of evidence supporting an effect of many social determinants of health, including racial background, employment and social support, on MS outcomes. It must be noted that many of the published studies were subject to bias, and screening tools and/or practical interventions that address these social determinants are, for the most part, lacking. The existing work does not fully explore the potential bidirectional and complex relationships between social determinants of health and MS, and the interpretation of findings is complicated by the interactions and intersections among many of the identified determinants. On the basis of the reviewed literature, we consider that, if effective interventions targeting social determinants of health were available, they could have substantial effects on MS outcomes. Therefore, funding for and focused design of studies to evaluate and address social determinants of health are urgently needed. Sections Key points• Addressing an individual's social determinants of health -that is, the conditions under which they are born, grow, live, work and age -could provide opportunities to reduce the burden of living with multiple sclerosis (MS).• Individual factors that may influence MS-related outcomes include sex, gender and sexuality, race and ethnicity, education and employment, socioeconomic status, and domestic abuse.• Societal infrastructures, including access to food, health care and social support, can also affect MS-related outcomes.• Awareness of the specific circumstances of a patient with MS might help neurologists deliver better care.• Social determinants of health are not static and can change according to wider sociopolitical contexts, as highlighted by the COVID-19 pandemic.• Rigorous studies of interventions to ameliorate the effects of poor social determinants on people with MS are urgently needed.Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author selfarchiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Review criteriaTo ensure an inclusive overview, we searched PubMed, Scopus, CINAHL through EBSCOhost, MEDLINE through OVID, all other Web of ...

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Brain health: The hidden casualty of a humanitarian crisis

Cited by 4 publications

References 9 publications

Fibromyalgia and mental health in rheumatoid arthritis: a cross-sectional prevalence study from the COVID-19 pandemic

Fibromyalgia and mental health in rheumatoid arthritis: a cross-sectional prevalence study from the COVID-19 pandemic

Perspective of schools of public health on war in Ukraine – reactions to military conflict in Europe and international cooperation

Social determinants of health in multiple sclerosis

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