Brain fetal magnetic resonance imaging to evaluate maturation of normal white matter during the third trimester of pregnancy

Letissier, Camille; Crombé, Amandine; Cherier, Lydie; Delmas, J; Chateil, Jean‐François

doi:10.1007/s00247-021-05064-1

Cited by 4 publications

(3 citation statements)

References 39 publications

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“…Numerous studies have reported that ADC values in the cerebral parenchyma could re ect differences in brain maturation and foetal brain growth [15,23,24]. In our study, the ADC differences between the cerebellar dysplasia and malformation groups did not differ signi cantly.…”

Section: Discussionsupporting

confidence: 39%

Prenatal magnetic resonance imaging of cerebellar dysplasia or malformations and coexistent malformations: A retrospective study in a single institution

Zhou

Huang

et al. 2022

Preprint

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Purpose: To clarify the prenatal magnetic resonance (MR) imaging characteristics of foetal cerebellar dysplasia/hypoplasia and developmental malformations and evaluate their diagnostic value. Methods: We retrospectively reviewed MR images of foetuses with suspected intracranial anomalies on screening ultrasound (US) on picture archiving communication system (PACS) servers within a five-year period in our institution. The main abnormal findings and coexistent anomalies were recorded by two experienced radiologists with census reading. The MRI and US results were paired and compared in each case. Results: We recruited 121 cases (average gestational week, 24.5 ± 4.7 weeks) with prenatal MR imaging, including sixty-two cases with simple cerebellar dysplasia or hypoplasia, thirty-one cases with other anomalies and twenty-eight cases with normal MR imaging findings. Cerebellar anomalies included intracranial haemorrhage, arachnoid cysts, Blake’s pouch cysts, Dandy-Walker malformation, cerebellar tonsil hernia and vermis absence. Coexistent cerebral malformations included hydrocephalus, cerebral haemorrhage, holoprosencephaly, brainstem/gyri malformation, ventriculomegaly and agenesis of the corpus callosum. Other detected systemic malformations included tethered cord syndromes (9 cases), club foot (1 case), cardiac malformation (1 case) and lip-palate cleft (1 case). Among 49 cases with both prenatal MR and US, MR imaging confirmed the diagnosis and/or provided more abnormal findings than US in 12 cases. Two dead babies after birth were recorded in cerebellar malformation group. Conclusion: Prenatal MR imaging could better show cerebellar anomalies and coexistent systemic malformations. As a complementary tool of US, MR imaging could help prenatal counselling and treatment selection at term.

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Section: Discussionsupporting

confidence: 39%

Prenatal magnetic resonance imaging of cerebellar dysplasia or malformations and coexistent malformations: A retrospective study in a single institution

Zhou

Huang

et al. 2022

Preprint

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“…Therefore, early detection of the blood supply to the patient's brain is of great significance for preventing the patient from suffering ischemic cerebral infarction and for improving the prognosis. Both computed tomography perfusion (CTP) and diffusion weighted imag-ing (DWI) of the whole brain can detect cerebral ischemia in patients [12,13]. At present, there are few clinical studies on the relationship between postoperative cerebral infarction and tumor size, location, and surgical process in patients with brain glioma, and relevant predictive indicators are lacking.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Radiographic Characteristics of Cerebral Infarction after Surgery in Patients with Glioma: A Retrospective Study

Zhu,

Zhao,

Shi

et al. 2024

Ann Ital Chir

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AIM: The aim of our study was to analyze risk factors for postoperative cerebral infarction in patients with glioma in our hospital, and to compare medical imaging techniques for early diagnosis of postoperative cerebral infarction. METHODS: A retrospective analysis was conducted on 178 patients (male: 78, female: 100) who underwent glioma surgery at our hospital between May 2015 and October 2023. They were divided into two groups based on the presence of postoperative cerebral infarction within 7 days: the cerebral infarction group (n = 85) and the non-cerebral infarction group (n = 93). Magnetic resonance imaging (MRI) was used to assess the location, distribution, and volume of the tumor before surgery. During the perioperative period, patient postoperative time, intraoperative blood loss, and other relevant data were documented. Computed tomography perfusion (CTP) and diffusion-weighted imaging (DWI) imaging techniques were employed to evaluate the occurrence, area, location, and shape of cerebral infarction. The imaging characteristics of postoperative cerebral infarction were noted. Apparent diffusion coefficient values, apparent diffusion coefficient (ADC) of whole-brain CTP parameters, cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), mean transit time (MTT), and DWI parameters were measured. The sensitivity and specificity of CTP, DWI, and their combined diagnosis for postoperative cerebral infarction were compared, with consistency assessed using the Kappa value. RESULTS: This study found that 85 patients (47.8%) experienced postoperative cerebral infarction. Significant risk factors included tumor location in the temporal lobe, tumor volume ≥23.57 cm3, number of surgeries >1, World Health Organization (WHO) grade >3, and intraoperative blood loss >79.83 mL (p < 0.05). Imaging examinations revealed that CTP combined with DWI diagnosis detected cerebral infarctions in 84 patients, showing lower CBF and CBV, and higher TTP, and MTT in the infarct group (p < 0.05). The Kappa values for CTP, DWI, and the combined diagnosis were 0.762, 0.833, and 0.937, respectively (p < 0.001). CONCLUSIONS: The prevalence of cerebral infarction in patients with glioma is high and is affected by many factors. Timely imaging examination can detect and predict the occurrence of cerebral infarction in patients after surgery, which is of great significance for improving the prognosis of patients.

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“…Previous studies have shown that diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) images, based on microscopic water diffusion, can help quantify fetal brain maturation and reveal diffuse white matter abnormalities (16)(17)(18). For example, Miller et al found abnormally high diffusion in the neonatal brain before corrective heart surgery (19).…”

Section: Introductionmentioning

confidence: 99%

Regional changes in brain apparent diffusion coefficient in fetuses with complex congenital heart disease and normal pregnancy assessed using diffusion-weighted imaging

Song

Zhu

et al. 2023

Front. Neurol.

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ObjectivesTo explore changes in brain apparent diffusion coefficient (ADC) in normal fetuses and fetuses with complex congenital heart disease (CHD) during the second and early third trimesters.MethodsThis single-center prospective study was conducted from May 2019 through October 2021. We measured and compared the mean ADC values between 23 fetuses with CHD and 27 gestational age (GA)-matched controls using covariance analyses. ADC density plots and histograms were used to compare brain characteristics. False-discovery rates (FDR, α = 0.05) correction was used for multiple testing.ResultsThe mean ADC in the frontal white matter, temporal white matter, parietal white matter, occipital white matter, cerebellar hemisphere, central area of the centrum semiovale, basal ganglia region, thalamus, and pons were not significantly different (all p > 0.05). Based on histogram analysis, there were no significant differences between the controls and fetuses with CHD after FDR correction. However, the ADC density plots showed significant heterogeneity between the controls and fetuses with CHD.ConclusionThe mean ADC values and ADC histogram analysis did not differ between the CHD and normal groups. The ADC density plots may provide supplementary information and improve the sensitivity for detecting early brain changes in fetuses with CHD.

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Brain fetal magnetic resonance imaging to evaluate maturation of normal white matter during the third trimester of pregnancy

Cited by 4 publications

References 39 publications

Prenatal magnetic resonance imaging of cerebellar dysplasia or malformations and coexistent malformations: A retrospective study in a single institution

Prenatal magnetic resonance imaging of cerebellar dysplasia or malformations and coexistent malformations: A retrospective study in a single institution

Prevalence and Radiographic Characteristics of Cerebral Infarction after Surgery in Patients with Glioma: A Retrospective Study

Regional changes in brain apparent diffusion coefficient in fetuses with complex congenital heart disease and normal pregnancy assessed using diffusion-weighted imaging

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