Brain-derived Tau for Monitoring Brain Injury in Acute Ischemic Stroke
Naomi Vlegels,
Fernando Gonzalez-Ortiz,
Nicoló Luca Knuth
et al.
Abstract:The evolution of infarcts varies widely among patients with acute ischemic stroke (IS) and influences treatment decisions. Neuroimaging is not applicable for frequent monitoring and there is no blood-based biomarker to track ongoing brain injury in acute IS. Here, we examined the utility of plasma brain-derived tau (BD-tau) as a biomarker for brain injury in acute IS. We conducted the prospective, observational Precision Medicine in Stroke [PROMISE] study with serial blood sampling upon hospital admission and … Show more
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