Brain atlas of children six to eight years old

Ortiz, J.P. Duque; González-Santos, Leopoldo; Rodríguez, Ll; Márquez, José Miguel Sánchez; Barrios, FA

doi:10.1016/s1053-8119(09)71579-4

Cited by 1 publication

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“…The relative numbers of TBI and bTBI cases seen in wounded military personnel returning from modern conflicts are larger than those seen in previous wars (Warden et al, 2009). This is most likely due to several factors, including advances in protective equipment (for example, thoracic armor reducing the potential for fatal pulmonary damage due to blast exposure) and in-the-field medical capabilities (Okie, 2005; Bass et al, 2012; Wood et al, 2012).…”

Section: Btbi Occurrencementioning

confidence: 92%

Functional MRI in the Investigation of Blast-Related Traumatic Brain Injury

et al. 2013

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This review focuses on the application of functional magnetic resonance imaging (fMRI) to the investigation of blast-related traumatic brain injury (bTBI). Relatively little is known about the exact mechanisms of neurophysiological injury and pathological and functional sequelae of bTBI. Furthermore, in mild bTBI, standard anatomical imaging techniques (MRI and computed tomography) generally fail to show focal lesions and most of the symptoms present as subjective clinical functional deficits. Therefore, an objective test of brain functionality has great potential to aid in patient diagnosis and provide a sensitive measurement to monitor disease progression and treatment. The goal of this review is to highlight the relevant body of blast-related TBI literature and present suggestions and considerations in the development of fMRI studies for the investigation of bTBI. The review begins with a summary of recent bTBI publications followed by discussions of various elements of blast-related injury. Brief reviews of some fMRI techniques that focus on mental processes commonly disrupted by bTBI, including working memory, selective attention, and emotional processing, are presented in addition to a short review of resting state fMRI. Potential strengths and weaknesses of these approaches as regards bTBI are discussed. Finally, this review presents considerations that must be made when designing fMRI studies for bTBI populations, given the heterogeneous nature of bTBI and its high rate of comorbidity with other physical and psychological injuries.

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