Brain activation in the presence of brain damage*1

Halsey, James H.; Blauenstein, Urs W.; Ea, Wilson; Wills, Edward L.

doi:10.1016/0093-934x(80)90071-1

Cited by 28 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This latter regional activation in the hemisphere ipsilateral to the paretic hand is in agreement with our observations. The rCBF variations in the injured hemisphere reported by Halsey et al, 9 although higher than in their control subjects, were not significant. However, they used fewer detectors (seven for each hemisphere) than we did, so that it is possible that they missed some local rCBF variations.…”

mentioning

confidence: 72%

“…In a study of hemiparetic patients with various degrees of disabilities, Halsey et al 9 did not observe any increase of rCBF in the injured hemisphere during movements of the contralateral hand; however, significant increases were present in the noninjured hemisphere in a region that included the hand motor area and the adjacent parietal region. This latter regional activation in the hemisphere ipsilateral to the paretic hand is in agreement with our observations.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Evidence of cortical reorganization in hemiparetic patients.

Brion

Demeurisse

Capon

1989

Stroke

View full text Add to dashboard Cite

We studied the mechanisms underlying the recovery of motor function of the hand using a bidimensionai xenon-133 inhalation technique to measure regional cerebral blood flow at rest and during the performance of a motor task (test condition). The regional cerebral blood flow patterns under rest and test conditions were compared in normal control and in stroke patients with either a cortico-subcortical or a deep-seated lesion. Functional recovery appears to depend upon cortical reorganization involving both hemispheres, particularly in both parietal regions in the subgroup of patients with cortico-subcortical lesions. (Stroke 1989;20:1079-1084

show abstract

mentioning

confidence: 72%

mentioning

confidence: 99%

Evidence of cortical reorganization in hemiparetic patients.

Brion

Demeurisse

Capon

1989

Stroke

View full text Add to dashboard Cite

show abstract

“…However, it increased with time and reached a normal pattern in the chronic stage. Other longitudinal studies with electrophysiological techniques [39, 59, 60]or CBF measurements [61]have also shown signs of progressive functional improvement on the damaged side following stroke. It seems that contribution of the affected hemisphere to motor recovery may increase during several weeks or months.…”

Section: Discussionmentioning

confidence: 99%

Bihemispheric Contribution to Motor Recovery after Stroke: A Longitudinal Study with Transcranial Doppler Ultrasonography

et al. 1999

View full text Add to dashboard Cite

Background: Both cerebral hemispheres seem to contribute to motor recovery after stroke. We studied the effect of motor activity on cerebral blood flow in both hemispheres at different stages of stroke evolution. Methods: Thirty patients with hemiplegic stroke and 30 controls were included. Patients were examined within the first week (T1), 1 month (T2) and 6 months after stroke (T3). All subjects performed a 2-min sequential thumb-to-finger opposition task while blood flow velocities in both middle cerebral arteries were measured with transcranial Doppler ultrasonography (TCD). Results: Contralateral movement caused a higher increase in blood flow velocity than ipsilateral movement in controls (p < 0.0001). On the healthy side, patients showed a striking increase with ipsilateral movement (affected hand), which was similar to the increase with contralateral movement (normal hand) at all stages. On the damaged side, the increase with contralateral movement (affected hand) was low and was similar to the increase with ipsilateral movement (normal hand) at T1 and T2; however, at T3 the increase with contralateral movement was higher and the pattern of response was similar to that found in controls. Conclusions: TCD can trace the evolution of brain motor output following stroke. Compensatory activation of the healthy side of the brain may be already present soon after stroke, whereas function of the damaged side may improve during several months.

show abstract

“…The xenon-133 was mixed with room air and administered via inhalation, in a concentration of 5 mCi/1, for a time of 1 minute, after which its clearance was monitored by a hemispheric array of 3 …”

Section: Methodsmentioning

confidence: 99%

“…2 The neuropsychological studies in the literature typically involve measurements of cerebral blood flow obtained during behavioral activation. 3 - 5 How well the results of these studies generalize to the more commonly used resting condition is unknown.…”

mentioning

confidence: 99%

Cerebral blood flow and neuropsychological asymmetries in unilateral stroke.

Brown

Ewing

Robertson

et al. 1991

Stroke

View full text Add to dashboard Cite

Background and Purpose: This study sought to determine the degree of agreement between asymmetries of neuropsychological functioning and nine methods of quantifying asymmetries of regional cerebral blood flow.Methods: The regional cerebral blood flow methods combined three markers of cerebral blood flow asymmetry (percent hemispheric difference, maximum percent probe-pair asymmetry, and number of probe-pair asymmetries) with three indexes of regional cerebral blood flow (fast compartment flow, initial slope index, and initial slope). Eleven patients with left hemispheric ischemic strokes and 13 with right hemispheric ischemic strokes were studied with the xenon-133 inhalation technique and neuropsychological tests.Results

show abstract

Brain activation in the presence of brain damage*1

Cited by 28 publications

References 5 publications

Evidence of cortical reorganization in hemiparetic patients.

Evidence of cortical reorganization in hemiparetic patients.

Bihemispheric Contribution to Motor Recovery after Stroke: A Longitudinal Study with Transcranial Doppler Ultrasonography

Cerebral blood flow and neuropsychological asymmetries in unilateral stroke.

Contact Info

Product

Resources

About