Brain abscess in childhood

Theophilo, F.; Markakis, E.; Theophilo, Lais; Dietz, H.

doi:10.1007/bf00270817

Cited by 18 publications

(6 citation statements)

References 29 publications

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“…are generally isolated as a part of mixed cultures in the case of otitis media infection or suppressed immune system in the ratio of 23% -33% (9). Several studies have reported that the growth ratio of anaerobic bacteria is nearly 25-30% in the case of brain abscess, and Bacteroides and Prevotella species were the most frequently isolated bacteria (10,11). The cases in which anaerobic bacteria are accounted for the development of brain abscess generally occur after middle ear and mastoid infection (12,13).…”

Section: Discussionmentioning

confidence: 99%

Mastoiditis, Brain Abscess and Sinus Thrombosis As Complications of Chronic Otitis Media: A Case Report

Maçin

İnkaya

Doğan

et al. 2016

Jundishapur J Microbiol

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Introduction: Brain abscess is a rare life-threatening focal intracerebral infection. The etiology of brain abscess depends on trauma, surgical intervention, and infection type. In this report, we present a case with brain abscess caused by Prevotella denticola after chronic otitis media infection. Case Presentation: A 27-year-old male patient presented a history of yellowish green ear drainage coloring his pillow for 10 years. One month before admission, he began to suffer from increased headache. He was first admitted to another hospital and treated with ceftriaxone for otitis media. He was referred to our hospital when a brain abscess was detected in cerebral magnetic resonance imaging (MRI). Meropenem and vancomycin treatment was stated empirically because of failure of the previous antibiotic therapy. The abscess was drained through a burr hole on the second day of admission. The aerobic culture of the pus resulted negative; however, black pigmented colonies were detected on anaerobic culture plates. The organism was identified as P. denticola via molecular typing targeting the 16S RNA gene. The postoperative period was complicated by left temporal hematoma that required surgical intervention; left transverse and sigmoid sinuses thrombosis were treated with enoxaparine. Because of the critical condition of the patient, de-escalation was not considered, and the patient received meropenem plus vancomycin for 6 weeks until discharge with complete cure. Conclusions: In conclusion, in spite of usually benign features, chronic otitis media may lead to serious complications such as brain abscess. Every effort should be made for microbiological diagnosis of the causative pathogen(s) for appropriate antibiotic treatment.

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Section: Discussionmentioning

confidence: 99%

Mastoiditis, Brain Abscess and Sinus Thrombosis As Complications of Chronic Otitis Media: A Case Report

Maçin

İnkaya

Doğan

et al. 2016

Jundishapur J Microbiol

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“…Case study is a method used when the research question requires a deep diving into the subject (Eisenhardt, 1989;Yin, 2015). While quantitative methods focus on literal replications to enhance the conclusions, qualitative methods rely on theoretical replication (Eisenhardt, 1989;Theóphilo & Martins, 2009;Yin, 2015).…”

Section: Methodsmentioning

confidence: 99%

How Technology Intelligence is Applied In Different Contexts?

Gonçalves

Almeida

2019

Int. J. Innov.

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Technology Intelligence is one of the many ways of applying Competitive Intelligence. As CI, TI intends to detect and process weak signals in order to identify opportunities and threats and provide actionable information. There is still a gap in reported cases of companies actually applying Technology Intelligence. This article intends to answer the research question: How companies build an actionable technology intelligence project? Case Study and Action-research approaches were applied for this research. The article describes two application cases: a research institute with a petrochemical industry as a client; and a private petrochemical industry. Companies seem to not know how to deal with Technology Intelligence. When outsourcing, they are more willing to pay for an extremely comprehensive project that not necessarily needs to be so deep and complex. When doing it internally, decision makers are not willing to wait and give the TI analysts resources to conduct a project in the right deepness and complexity. It seems like a “goldilocks problem” applied to Technology Intelligence.

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“…They are potentially curable but can be difficult lesions to treat. The m o r t a l i t y in brain abscess has fallen from 4 0 -5 0 % in the p r e -C T era < 12, 22, 36, 38 to 0--20% in recent years 11, 34,37,42,49,50. The difficulties that m a y be encountered in m a n a g i n g a single brain abscess increase when m o r e than one are present 51. Prior to 1975, the incidence o f multiple brain abscesses was reported as 5 -1 5 % 4, 12, 22.…”

Section: Introductionmentioning

confidence: 99%

Multiple pyogenic brain abscesses

Sharma

Khosla

et al. 1995

Acta neurochir

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Thirty eight patients with multiple pyogenic brain abscesses constituted 11% of all the brain abscesses treated during a 12 year period. Sixty per cent (23) of the patients were in the first two decades of life, including 9 (24%) infants. The clinical presentation was similar to brain abscess in general. 21 patients had altered "sensorium" at the time of admission. Otogenic brain abscesses were the commonest (26%), followed by those associated with congenital cyanotic heart disease (18%). The abscesses were invariably large in size. The pus was sterile on culture in 11 (29%) patients, while Staphylococcus aureus was the commonest organism grown in 9 (24%) patients. Aspiration of the pus was required as a life saving measure, to control raised intracranial pressure, in 29 (76%) patients. Twelve (32%) of these patients underwent secondary excision of the abscess capsule. The overall mortality was 32% with failure to control intracranial and systemic infection as the major causes of mortality. Level of consciousness at the time of admission was the most significant factor affecting the outcome. Surgery has a definite therapeutic and life saving role in the management of multiple pyogenic brain abscesses. A systematic treatment plan for multiple abscesses is proposed.

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Brain abscess in childhood

Cited by 18 publications

References 29 publications

Mastoiditis, Brain Abscess and Sinus Thrombosis As Complications of Chronic Otitis Media: A Case Report

Mastoiditis, Brain Abscess and Sinus Thrombosis As Complications of Chronic Otitis Media: A Case Report

How Technology Intelligence is Applied In Different Contexts?

Multiple pyogenic brain abscesses

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