Brain abscess caused by streptococcus intermedius: two case reports

Histone-like DNA binding protein of Streptococcus intermedius induces the expression of pro-inflammatory cytokines in human monocytes via activation of ERK1/2 and JNK pathways

“…Streptococcus intermedius is a commensal in the human oral cavity, and can cause purulent infections in the mouth and internal organs, such as the brain and liver (Yamamoto et al, 1999;Claridge et al, 2001;Wagner et al, 2006). To date, few components of S. intermedius have been identified as potential virulence factors.…”

Biofilm formation and autoinducer‐2 signaling in Streptococcus intermedius: role of thermal and pH factors

“…In the oral cavity, acute third molar pericoronitis (16) and periapical abscesses are frequently associated with the S. anginosus group (8). S. intermedius is frequently associated with chronic periodontitis and upper‐body abscesses, especially brain abscesses (22, 30).…”

Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis

“…32,40,50,52 The recurrences required repeated craniotomy; however, an examination of stained tissue and cultures revealed that the aspirates contained only numerous leukocytes without microorganisms. Three days postoperatively, however, three of the five patients experienced a paradoxical deterioration with imaging evidence of recurrence of the lesion.…”