Brachioradial pruritus

Veien, Niels K.; Hattel, Thais; Laurberg, Grete; Spaun, Eva

doi:10.1067/mjd.2001.112912

Cited by 23 publications

(27 citation statements)

References 12 publications

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“…Histopathologic examination of skin areas with normal appearance were essentially normal, arguing against systemic or subclinical skin abnormalities. Among the differential diagnoses for the skin presentations detected are neurotic excoriations [16], atopic dermatitis, brachioradial pruritis [17], [18], and arthropod bites.…”

Section: Discussionmentioning

confidence: 99%

Clinical, Epidemiologic, Histopathologic and Molecular Features of an Unexplained Dermopathy

et al. 2012

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BackgroundMorgellons is a poorly characterized constellation of symptoms, with the primary manifestations involving the skin. We conducted an investigation of this unexplained dermopathy to characterize the clinical and epidemiologic features and explore potential etiologies.MethodsA descriptive study was conducted among persons at least 13 years of age and enrolled in Kaiser Permanente Northern California (KPNC) during 2006–2008. A case was defined as the self-reported emergence of fibers or materials from the skin accompanied by skin lesions and/or disturbing skin sensations. We collected detailed epidemiologic data, performed clinical evaluations and geospatial analyses and analyzed materials collected from participants' skin.ResultsWe identified 115 case-patients. The prevalence was 3.65 (95% CI = 2.98, 4.40) cases per 100,000 enrollees. There was no clustering of cases within the 13-county KPNC catchment area (p = .113). Case-patients had a median age of 52 years (range: 17–93) and were primarily female (77%) and Caucasian (77%). Multi-system complaints were common; 70% reported chronic fatigue and 54% rated their overall health as fair or poor with mean Physical Component Scores and Mental Component Scores of 36.63 (SD = 12.9) and 35.45 (SD = 12.89), respectively. Cognitive deficits were detected in 59% of case-patients and 63% had evidence of clinically significant somatic complaints; 50% had drugs detected in hair samples and 78% reported exposure to solvents. Solar elastosis was the most common histopathologic abnormality (51% of biopsies); skin lesions were most consistent with arthropod bites or chronic excoriations. No parasites or mycobacteria were detected. Most materials collected from participants' skin were composed of cellulose, likely of cotton origin.ConclusionsThis unexplained dermopathy was rare among this population of Northern California residents, but associated with significantly reduced health-related quality of life. No common underlying medical condition or infectious source was identified, similar to more commonly recognized conditions such as delusional infestation.

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Section: Discussionmentioning

confidence: 99%

Clinical, Epidemiologic, Histopathologic and Molecular Features of an Unexplained Dermopathy

et al. 2012

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“…Twenty-one of the patients had been included in a previous report ( 1 ). Inclusion criteria: the diagnosis of BRP was made on clinical grounds and based on the patients' description of itching, tingling, and/or a burning sensation on the skin on the lateral aspects of the upper arms (on the dorsal aspect of the forearms and/or on the shoulders).…”

Section: Methodsmentioning

confidence: 99%

“…I Acquired Cl inhibitor deficiency (AAE) is a rare syndrome with features similar to those of hereditary angioedema (HAE), but differirig in its later onset and lack of family history. AAE is characterized by increased consumption of C1 inhibitor associated with lymphoproliferative or malignant disorders, autoimmune or infectious diseases (1,2). In Cl inhibitor deficiency two different skin manifestations can be seen:¡angioedema and erythema marginatum.…”

Section: Rapid Resolution Of Erythema Marginatum After Icatibant In Amentioning

confidence: 99%