Brachial Artery Flow-Mediated Vasodilation Is Correlated with Coronary Vasomotor and Fibrinolytic Responses Induced by Bradykinin

Association of Plasma Dehydroepiandrosterone-Sulfate Levels with Endothelial Function in Postmenopausal Women with Coronary Risk Factors

“…In this cross-sectional study, plasma DHEA-S levels were positively correlated with %FMD, a surrogate marker of clinical atherosclerosis that reflects endothelial function (18,19). Adjustment for potential confounders such as age, coronary risk factors and nitroglycerin-induced dilation of the brachial artery had little influence on the results.…”

Patients With Obstructive Sleep Apnea Exhibit Impaired Endothelial Function After Myocardial Infarction

“…12,13 OSA is a common comorbidity in patients with MI; however, there is no information about the implications of OSA for the long-term prognosis of patients post MI. Brachial artery FMD is strongly associated with coronary artery endothelial function 5 and has been used in clinical practice as a measure of endothelial function. Among men who had an acute coronary syndrome without ST elevation, those who had FMD , 1.9% were more likely to have cardiovascular events.…”

“…4 Moreover, FMD is closely related to coronary endothelial function. 5 Prior studies have shown diffuse endothelial dysfunction in patients with long-term 6 and short-term coronary syndromes. 7 Epidemiologic and experimental data suggest that patients with OSA have impaired endothelial function, a mechanism that may help explain the association between OSA and cardiovascular diseases.…”

Beneficial Effect of T-Type Calcium Channel Blockers on Endothelial Function in Patients with Essential Hypertension

“…Endothelium-dependent vascular relaxation has been found to be impaired in brachial (2,3), renal (4), and coronary arteries (5) of patients with essential hypertension, since oxidative stress causes a reduction in NO availability. Moreover, endothelial dysfunction and oxidative stress are predictors of cardiovascular events (6). It is important for the establishment of an appropriate therapeutic strategy to determine whether or not antihypertensive treatment improves endothelial dysfunction in addition to lowering blood pressure in patients with essential hypertension.…”