BOX Structures with Additional Coordination Sites: Potential Ligands for Bifunctional Catalysis

Abstract

The synthesis of four new bis(oxazoline) (BOX) derivatives bearing two additional coordination sites at the 4,4′‐positions is presented. As these BOX scaffolds contain an unsubstituted methylene bridge, they should be capable of forming neutral metal complexes. Thus, these molecules are very interesting ligands for bifunctional catalysis. In addition, one BOX scaffold bearing two azide moieties was successfully employed in copper‐free 1,3‐dipolar cycloaddition reactions. The resulting products have yet again high ligand potential.