“Bowenoid” leukoplakia in the anal region

Abstract

A case of "bowenoid" leukoplakia in the anal region of a 31-year-old woman is presented to our knowledge for the first time in the literature. Clinically the lesion appeared as a "simple" leukoplakia. Although excision of the lesion was performed as histologically shown in toto, three recurrences followed. Both retinoid therapy and local treatment with 5-fluorouracil were unsuccessful, whereas radiation therapy apparently cured the patient.

Oral leukoplakia: demographic, clinical and histopathological characteristics

“…12 Although OL was originally thought to be more prevalent in men because of tobacco consumption, in recent years, the disparity between OL rates in men and women has diminished. 5 In their study, Starzynska et al, screened 55911 patients from between 1999 and 2009, finding 204 OL patients for epidemiological and clinical analysis; they ascertained a male population of 49% (n=100) and female population of 51% (n=104). 13 In another study carried out by Liu et al, of 218 patients, 50.5% (n=110) patients were male and 49.5% (n=108) were female.…”

“…4 OL lesions can be located in any part of the mouth; however, the most common site is in the buccal mucosa. 5 Fig. 1.…”