Bowel preparation for the total colonoscopy by 2,000 ml of balanced lavage solution (Golytely) and sennoside

Iida, Yoshiro; Miura, Shoji; Asada, Yasuyuki; Fukuoka, Kennichi; Toya, Daishu; Tanaka, Nobuyoshi; Fujisawa, Masakiyo

doi:10.1007/bf02806525

Cited by 27 publications

(25 citation statements)

References 3 publications

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“…However, poor tolerance and adverse effect were often found in the bowel preparation of colonoscopy for elderly patients and those with constipation, since they are often required to drink larger volumes of lavage solution prior to the bowel cleansing procedure. Both polyethylene glycol (PEG) electrolyte solution and magnesium citrate (MGC) solution have been widely used in Japan as lavage solutions for bowel cleansing [1,2,3,4]. About 2,000 ml of these solutions are usually required for adequate bowel preparation.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Prokinetic Agents in Improving Bowel Preparation for Colonoscopy

Mishima

Amano²,

Okita³

et al. 2008

Digestion

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Background and Aim: Colonoscopy plays an important role in the diagnosis and treatment of gastrointestinal illness in both Western countries and Japan. However, preparative bowel cleansing for colonoscopy is frequently troublesome for elderly and/or constipated patients, since they must drink larger volumes of lavage solution for adequate cleansing. We investigated the use of prokinetic agents for improving the efficacy and tolerability of bowel cleansing prior to colonoscopy. Methods: 613 patients were divided into two groups according to oral lavage solution used (polyethylene glycol or magnesium citrate), and were further randomized to receive either vehicle (100 ml water) alone, vehicle with 5 mg mosapride citrate, or vehicle with 50 mg itopride hydrochloride 30 min before administration of lavage solution. Experimental parameters included bowel cleansing quality, times to first defecation and completion of bowel cleansing, and incidence of uncomfortable abdominal symptoms during colonoscopy preparation. Results: Administration of mosapride citrate or itopride hydrochloride prior to oral lavage solution did not significantly improve bowel cleansing quality. However, statistically significantly fewer uncomfortable abdominal symptoms were found in patients who received mosapride citrate or itopride hydrochloride versus vehicle alone. Conclusion: Prokinetic agents effectively decreased the incidence of uncomfortable abdominal symptoms experienced during colonoscopy preparation.

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Section: Introductionmentioning

confidence: 99%

Efficacy of Prokinetic Agents in Improving Bowel Preparation for Colonoscopy

Mishima

Amano²,

Okita³

et al. 2008

Digestion

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“…Like bisacodyl, senna can also be used as an adjunct to PEG-ELS. It has also been shown to reduce the amount of PEG-ELS required for effective bowel preparation (Iida et al, 1992).…”

Section: Sennamentioning

confidence: 99%

Preparing for Colonoscopy

Deepak¹,

Sifuentes²,

Sherid³

et al. 2011

Endoscopic Procedures in Colon and Rectum

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Endoscopic Procedures in Colon and Rectum 18 followed by repeated procedures. In a study of 200 consecutive outpatient colonoscopies, imperfect bowel preparation resulted in a 12% increase in costs at a university hospital and 22% increase in costs at a public hospital (Rex et al., 2002). Types of bowel preparationsThe ideal colon preparation should rapidly and reliably cleanse the colon of fecal material while having no effect on the gross or microscopic appearance of the colon (Wexner et al., 2006). It should require a short period for ingestion and evacuation, cause no discomfort, and produce no significant fluid or electrolyte shifts while also being palatable, simple, and inexpensive. Agents used for bowel preparation can be divided into three main categories according to their mechanism of action, these being isosmotic, hyperosmotic, and adjunctive preparations. Polyethylene glycol-electrolyte lavage solutions (PEG-ELSs) and sodium phosphate (NaP) formulations are among the most commonly used. 2.2

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“…Recently, the adjunctive use of low dose senna with PEG solutions has been demonstrated to improve the quality of bowel preparation 36 and to reduce the amount of PEG-ELS required for effective bowel preparation. 41 . This also reduces the abdominal pain reported with high dose senna.…”

Section: Stimulant Laxativesmentioning

confidence: 99%