Bowel preparation before colonoscopy in the era of mass screening for colo-rectal cancer: A practical approach

Parente, F.; Marino, B.; Crosta, C.

doi:10.1016/j.dld.2008.06.005

Cited by 52 publications

(35 citation statements)

References 57 publications

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“…There is still a need to increase the overall acceptability of bowel preparation for colonoscopy and reduce the burden and impact on productivity and daily living with the ultimate objective to improve the attitude toward colonoscopy within the colon cancer screening programs [8] .…”

Section: Introductionmentioning

confidence: 99%

Same-day 2-L PEG-citrate-simethicone plus bisacodylvssplit 4-L PEG: Bowel cleansing for late-morning colonoscopy

Leone

Tamayo²,

Fiori³

et al. 2013

WJGE

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AIM:To evaluate the efficacy, tolerability, acceptability and feasibility of bisacodyl plus low volume polyethyleneglycol-citrate-simeticone (2-L PEG-CS) taken the same day as compared with conventional split-dose 4-L PEG for late morning colonoscopy. METHODS:Randomised, observer-blind, parallel group, comparative trial carried out in 2 centres. Out patients of both sexes, aged between 18 and 85 years, undergoing colonoscopy for diagnostic investigation, colorectal cancer screening or follow-up were eligible. The PEG-CS group received 3 bisacodyl tablets (4 tablets for patients with constipation) at bedtime and 2-L PEG-CS in the morning starting 5 h before colonoscopy. The control group received a conventional 4-L PEG formulation given as split regimen; the morning dose was taken with the same schedule of the low volume preparation. The Ottawa Bowel Preparation Scale (OBPS) score was used as the main outcome measure. RESULTS:A total of 164 subjects were enrolled and 154 completed the study; 78 in the PEG-CS group and 76 in the split 4-L PEG group. The two groups were comparable at baseline. The OBPS score in the PEG-CS group (3.09 ± 2.40) and in the PEG group (2.39 ± 2.55) were equivalent (difference +0.70; 95%CI: -0.09-1.48). This was confirmed by the rate of successful bowel cleansing in the PEG-CS group (89.7%) and in the PEG group (92.1%) (difference -2.4%; 95%CI: -11.40-6.70). PEG-CS was superior in terms of mucosa visibility compared to PEG (85.7% vs 72.4%, P = 0.042). There were no significant differences in caecum intubation rate, time to reach the caecum and withdrawal time between the two groups. The adenoma detection rate was similar (PEG-CS 43.6% vs PEG 44.7%). No serious adverse events occurred. No difference was found in tolerability of the bowel preparations. Compliance was equal in both groups: more than 90% of subjects drunk the whole solution. Willingness to repeat the same bowel preparations was about 90% for both regimes. CONCLUSION:Same-day PEG-CS is feasible, effective as split-dose 4-L PEG for late morning colonoscopy and does not interfere with work and daily activities the day before colonoscopy. Key words: Bowel preparation; Polyethyleneglycol; Simethicone; Ottawa Bowel Preparation Scale; Colonoscopy Core tip: The timing of bowel preparation is fundamental for high quality colonoscopy and also for patient satisfaction. Split-dose preparation improves the rate of adequate cleansing and patient compliance. This study shows that the same-day low volume polyethyleneglycol-citrate-simeticone (PEG-CS) plus bisacodyl tablets is feasible, and as effective as split 4-L PEG. The low volume bowel preparation taken the same day of the exam may be an attractive option for late morning September 16, 2013|Volume 5|Issue 9|

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Section: Introductionmentioning

confidence: 99%

Same-day 2-L PEG-citrate-simethicone plus bisacodylvssplit 4-L PEG: Bowel cleansing for late-morning colonoscopy

Leone

Tamayo²,

Fiori³

et al. 2013

WJGE

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“…Many agents have been used in colonoscopy preparation (13,14), and the efficacies of colon preparatory regimens have been compared in many studies (15,16). It has been demonstrated in some studies that polyethylene glycol (PEG) is a faster, more effective and better-tolerated method for cleansing the colon (1,17,18). In 2006, the Association of American Colon and Rectal Surgery (ASCRS), American Gastrointestinal Endoscopy Association (ASGE) and American Gastrointestinal and Endoscopic Surgery Association (SAGES) prepared a consensus documentary for intestinal preparation before colonoscopy (1).…”

Section: Discussionmentioning

confidence: 99%

The efficacy and safety of colonoscopy preparation with oral sodium phosphate in elderly patients

Yakut

Çınar²,

Seven³

et al. 2010

Turk J Gastroenterol

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“…The quality of the preparation has been a recent development (8). If the quality of preparation for colonoscopy is arguably dependent patients, it does not mean totally independent gastroenterologist.…”

Section: The Quality Of Bowel Preparationmentioning

confidence: 99%

Quality Indicators for Colonoscopy Procedures

Pommaret¹,

Leblanc²,

Chaussade³

2011

Applications and Experiences of Quality Control

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Bowel preparation before colonoscopy in the era of mass screening for colo-rectal cancer: A practical approach

Cited by 52 publications

References 57 publications

Same-day 2-L PEG-citrate-simethicone plus bisacodylvssplit 4-L PEG: Bowel cleansing for late-morning colonoscopy

Same-day 2-L PEG-citrate-simethicone plus bisacodylvssplit 4-L PEG: Bowel cleansing for late-morning colonoscopy

The efficacy and safety of colonoscopy preparation with oral sodium phosphate in elderly patients

Quality Indicators for Colonoscopy Procedures

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