Bowel‐Associated‐Dermatosis‐Arthritis Syndrome (BADAS) as early presentation of ulcerative colitis in an adolescent girl

Johns, Hannah R; Shetty, Nayha; Cash, Joshua; Patel, Tejesh; Pourciau, Crystal Y.

doi:10.1111/pde.14954

Cited by 3 publications

(14 citation statements)

References 5 publications

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“…Tender, erythematous plaques and nodules are often seen in Sweet's syndrome and erythema nodosum, whereas pustules and ulcerated nodules may be the initial presentation of pyoderma gangrenosum in patients with IBD. However, the association between general malaise, diarrhea, and polyarthritis in our patient was more consistent with the diagnosis of BADAS 5 . The presence of cutaneous abscesses and neutrophilic infiltrates is also a characteristic of aseptic abscess syndrome.…”

Section: Discussionsupporting

confidence: 85%

“…The presence of cutaneous abscesses and neutrophilic infiltrates is also a characteristic of aseptic abscess syndrome. Nevertheless, this entity features abscesses in internal viscera, which our patient did not exhibit 5 . Histological findings excluded the diagnosis of metastatic Crohn's disease, which would display noncaseating granulomas.…”

Section: Discussionmentioning

confidence: 51%

“…However, the association between general malaise, diarrhea, and polyarthritis in our patient was more consistent with the diagnosis of BADAS. 5 The presence of cutaneous abscesses and neutrophilic infiltrates is also a characteristic of aseptic abscess syndrome. Nevertheless, this entity features abscesses in internal viscera, which our patient did not exhibit.…”

Section: Case Presentationmentioning

confidence: 99%

“…Nevertheless, this entity features abscesses in internal viscera, which our patient did not exhibit. 5 Histological findings excluded the diagnosis of metastatic Crohn's disease, which would display noncaseating granulomas.…”

Section: Case Presentationmentioning

confidence: 99%

“…1 The diagnosis of BADAS can be challenging because of the lack of defined diagnostic criteria and the fact that BADAS can mimic a number of different dermatoses. 5 Histologically, BADAS is characterized by a marked neutrophilic infiltrate that can extend from the epidermis into the adipose tissue, involving lobules and septa. These findings, however, are not pathognomonic of BADAS and could be identical to those of Sweet's syndrome and other neutrophilic dermatoses.…”

Section: Case Presentationmentioning

confidence: 99%

See 4 more Smart Citations

Pustules, arthritis, and fever in a patient with Crohn's disease

Alturo‐Pons,

Carmona‐Rocha,

Rusiñol

et al. 2024

Int J Dermatology

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 51%

Section: Case Presentationmentioning

confidence: 99%

Section: Case Presentationmentioning

confidence: 99%

Section: Case Presentationmentioning

confidence: 99%

See 3 more Smart Citations

Pustules, arthritis, and fever in a patient with Crohn's disease

Alturo‐Pons,

Carmona‐Rocha,

Rusiñol

et al. 2024

Int J Dermatology

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The Bowel-Associated Arthritis–Dermatosis Syndrome (BADAS): A Systematic Review

Aromolo,

Simeoli,

Maronese

et al. 2023

Metabolites

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Bowel-associated arthritis–dermatosis syndrome (BADAS) is a rare neutrophilic dermatosis that was first described in 1971 in patients who underwent bypass surgery for obesity. Over the years, the number of reported cases associated with medical gastroenterological conditions, particularly inflammatory bowel disease (IBD), has progressively increased. To date, there are no systematic reviews in the literature on BADAS. The design of an a priori protocol was based on PRISMA guidelines, and a search of PubMed and Scopus databases was conducted for articles published between 1971 and 2023 related to the topic. Fifty-one articles including 113 patients with BADAS were analyzed in this systematic review. Bariatric surgery and IBD were the most frequently reported causes of BADAS, accounting for 63.7% and 24.7% of all cases, respectively. A total of 85% of cases displayed the typical dermatological presentation, including urticarial maculopapular lesions centered by a vesicopustule, with the majority of lesions located on the upper limbs (73.5%). Polyarthralgia or localized arthritis were always present. Atypical presentations included cellulitis-like, erythema-nodosum-like, Sweet-syndrome-like and pyoderma-gangrenosum-like manifestations. Gastrointestinal symptoms were frequently observed in IBD-related cases (67.9%). The histopathology showed a neutrophilic infiltrate (96.6%). The most commonly used treatment regimens consisted of systemic corticosteroids, metronidazole and tetracyclines, either alone or in combination. A relapsing–remitting course was observed in 52.1% of patients. In conclusion, BADAS is a neutrophilic dermatosis that presents with a wide variety of cutaneous manifestations, both typical and atypical. Gastrointestinal symptoms are frequently observed, particularly in cases related to IBD. The histopathology is clear but not specific compared with other neutrophilic dermatoses. The diagnosis can be challenging, but the relapsing–remitting course and the strong association with polyarthralgia and gastrointestinal disease can aid in the diagnosis.

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Bowel-associated dermatosis-arthritis syndrome (BADAS): a narrative review

Czajkowski,

Lipska,

Watoła

et al. 2023

pdia

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Bowel-associated dermatosis-arthritis syndrome is a neutrophilic dermatosis presenting with flu-like symptoms, arthritis and skin lesions. The type of skin presentation varies although typically consists of red patches progressing into papulopustular-type lesions. Initially, the pathogenesis of the disease was linked exclusively to bariatric surgery, but more recent reports indicate the role of gastrointestinal diseases resulting in bacterial overgrowth and consequent translocation of bacteria into the bloodstream. The disease may resolve spontaneously, however sometimes requires a treatment aimed at managing inflammation and excessive bacterial overgrowth, and therefore antibiotic therapy, immunosuppressive drugs, biological treatment and sometimes intestinal surgeries are applied.

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Bowel‐Associated‐Dermatosis‐Arthritis Syndrome (BADAS) as early presentation of ulcerative colitis in an adolescent girl

Cited by 3 publications

References 5 publications

Pustules, arthritis, and fever in a patient with Crohn's disease

Pustules, arthritis, and fever in a patient with Crohn's disease

The Bowel-Associated Arthritis–Dermatosis Syndrome (BADAS): A Systematic Review

Bowel-associated dermatosis-arthritis syndrome (BADAS): a narrative review

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