Bowel‐associated dermatosis–arthritis syndrome: another cutaneous manifestation of inflammatory intestinal disease

Truchuelo, M.; Alcántara, Javier; Vañó‐Galván, Sergio; Jaén, Pedro; Moreno, Carmen

doi:10.1111/j.1365-4632.2011.05149.x

Cited by 17 publications

(9 citation statements)

References 7 publications

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“…In most cases after persisting for approximately 1 week, each flare spontaneously resolves without scarring and can be associated with relapses every 4 to 6 weeks. 1 , 2 Eruptions of BADAS can be accompanied by nonerosive tenosynovitis, polyarthralgias, diarrhea, and flu-like symptoms such as myalgias and fever. 2 …”

Section: Discussionmentioning

confidence: 99%

“…Other diagnoses to consider could include pyoderma gangrenosum, leukocytoclastic vasculitis, rheumatoid neutrophilic dermatosis, dermatitis herpetiformis, and bacterial and viral infections such as subacute endocarditis and gonococcal sepsis. 1 , 3 …”

Section: Discussionmentioning

confidence: 99%

“…Bowel-associated dermatosis-arthritis syndrome (BADAS) is a recurrent and episodic neutrophilic dermatosis characterized by erythematous macules, which quickly evolve into papules and vesiculopustules on the trunk and upper extremities. 1 , 2 Originally only associated with bariatric surgery, 3 BADAS is now reported secondary to gastrointestinal disease. 4 Although typically seen in adults, we report a case of a 4-year-old patient with numerous scattered hemorrhagic vesicles and flu-like symptoms whose biopsy specimen revealed a neutrophilic infiltrate consistent with BADAS.…”

Section: Introductionmentioning

confidence: 99%

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Bowel-associated dermatosis-arthritis syndrome (BADAS) in a pediatric patient

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bowel-associated dermatosis-arthritis syndrome (BADAS) in a pediatric patient

et al. 2016

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“…Systemic and topical antibiotics are ineffective but may be useful for treating superinfection of opened skin lesions. 118,119 Oral Aphthous Ulcers Oral aphthous ulcers are reactive lesions frequently encountered in patients with IBD. Because nutritional deficiencies in iron, folic acid, and vitamin B12 secondary to active IBD predispose toward aphthous ulcer formation, oral aphthae had classically been considered as multifactorial in origin.…”

Section: Sweet's Syndromementioning

confidence: 99%

Cutaneous Manifestations in Patients With Inflammatory Bowel Diseases

Marzano

Borghi

Stadnicki

et al. 2014

Inflammatory Bowel Diseases

116

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The skin is one of the most common extraintestinal organ system affected in patients with inflammatory bowel disease (IBD), including both Crohn's disease and ulcerative colitis. The skin manifestations associated with IBD are polymorphic and can be classified into 4 categories according to their pathophysiology: (1) specific, (2) reactive, (3) associated, and (4) induced by IBD treatment. Cutaneous manifestations are regarded as specific if they share with IBD the same granulomatous histopathological pattern: perianal or metastatic Crohn's disease (commonly presenting with abscesses, fistulas or hidradenitis suppurativa-like features) is the prototype of this setting. Reactive cutaneous manifestations are different from IBD in the histopathology but have close physiopathological links: pyoderma gangrenosum, a neutrophil-mediated autoinflammatory skin disease typically manifesting as painful ulcers, is the paradigm of this group. Among the cutaneous diseases associated with IBD, the most commonly seen are erythema nodosum, a form of panniculitis most commonly involving bilateral pretibial areas, and psoriasis, a T helper 1/T helper 17-mediated erythematous squamous inflammatory disease. Finally, the number of cutaneous adverse reactions because of IBD therapies is progressively increasing. The most frequent drug-induced cutaneous manifestations are psoriasis-like, eczema-like, and lichenoid eruptions, as well as cutaneous lupus erythematosus for biologics, and nonmelanoma skin cancer, mainly basal cell and squamous cell carcinomas for thiopurines.

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“…Laboratory indexes such as RF, immune globulin and uric acid are all within normal limits, however, some patients may have elevated cryoglobulin (Patton et al 2009 ). In microbiological examination, both of blood culture and rash fester culture results are negative (Truchuelo et al 2013 ). The dermal pathology of BADAS is usually the same as acute febrile neutrophilic dermatosis (SWEET) syndrome.…”

Section: Discussion and Evaluationmentioning

confidence: 99%

Is it bowel-associated dermatosis-arthritis syndrome induced by small intestinal bacteria overgrowth?

Zhao

Shi

et al. 2016

SpringerPlus

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IntroductionBowel-associated dermatosis-arthritis syndrome is rare systemic diseases characterized by a prodrome of fever, chills, and influenza-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. It is reported to be occurred in Intestinal bypass surgery and inflammatory bowel disease.Case descriptionHerein, we described a 29-years-old man with Bowel-associated dermatosis-arthritis syndrome. He had no history of gastrointestinal surgery and inflammatory bowel disease. Distribution of the gut bacterial flora showed small intestinal bacterial overgrowth.Discussion and EvaluationIt is rarely form as Non-intestinal bypass road and non-inflammatory bowel disease was induced by small intestinal bacteria overgrowth.ConclusionsWe concluded that Immuno-inflammatory response to overgrowth of intestinal bacterial antigen induce the clinical symptoms of bowel-associated dermatosis-arthritis syndrome.

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Bowel‐associated dermatosis–arthritis syndrome: another cutaneous manifestation of inflammatory intestinal disease

Cited by 17 publications

References 7 publications

Bowel-associated dermatosis-arthritis syndrome (BADAS) in a pediatric patient

Bowel-associated dermatosis-arthritis syndrome (BADAS) in a pediatric patient

Cutaneous Manifestations in Patients With Inflammatory Bowel Diseases

Is it bowel-associated dermatosis-arthritis syndrome induced by small intestinal bacteria overgrowth?

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