Bovine colostrum: A source of bioactive compounds for prevention and treatment of gastrointestinal disorders

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

“…Food processing is intended to ensure the quality and safety of food while minimizing nutritional and bioactive constituent loss and maximizing deterioration of pathogenic and spoilage microorganisms with extended shelf life [ 31 ]. The industrial use of bovine colostrum on a large scale is limited due to its low coagulation temperature, microbial load, and other issues generated during processing and storage [ 32 , 33 , 34 ]. Several processing strategies, including pasteurization, microwave, spray drying, freezing, thermal treatments, drying techniques (freeze and spray drying), filtering, membrane processing, HPP, and pulse electric field, have been documented in the literature to reduce microbial burden in BC [ 35 , 36 , 37 ].…”

Bioactive compounds, nutritional profile and health benefits of colostrum: a review

“…Growth factors possess resistance for the heat treatment (up to 60 °C). Several newer technologies are being developed to extract such compounds from the bovine colostrum (Gomes et al 2021 ). The concentration of growth factors varies with the species and also within the species.…”

“…The major growth factors involves β-cellulin (BTC), epidermal growth factor (EGF), β1-transforming growth factor (TGF-β1), insulin-like growth factor (IGF-1), fibroblast growth factor 1 & 2 (FGF1 & FGF2) and platelet-derived growth factor (PDGF) (McGrath et al 2016 ). Polypeptides like TGF-β1, EGF and IGF-1 have the ability to be partially degraded or absorbed well intact in GI tract (Gomes et al 2021 ).…”

“…It is identified by lower absorption of nutrients and diarrhea and onset of weight-loss and malnutrition (Jin & Gramlich, 2019 ). Gomes et al ( 2021 ) studied the effect of supplementation of piglets with protein concentrate obtained from BC and promising results were derived such as improved levels of IGF-1, muscle hypertrophy and the binding proteins. So, supplementation of protein concentrate of BC can be alternative in treatment and prevention of Short Bowl Syndrome.…”

“…Colostrum is profuse in bioactive compounds like immunoglobulins, growth factors, lysozymes, lectoferrin, lactoperoxidase and designed in such a way that it dispense the new born with passive immunity against pathogens. It also possesses elevated levels of fats, proteins, minerals and vitamins (Gomes et al 2021 ). There are many evidences contributing to the verity that BC can be a valuable commodity for the treatment of diversified medical constraints in both adults and children (Bagwe-Parab et al 2020 ; Ulfman et al 2018 ).…”