Bovine Collagen Xenograft Repair of Extensive Surgical Scalp Wounds With Exposed Calvarium in the Elderly

Abstract

In patients with postsurgical scalp defects with exposed calvarium, collagen xenograft placement may expedite second-intention healing and offer other advantages in the elderly population.

Quantifying Utilization of Skin Substitutes by Mohs Micrographic Surgeons: A Cross-Sectional Analysis of Medicare Data

“…Unfortunately, there are few prospective studies quantifying the benefits of xenografts, but there are some data in small studies to suggest that they may provide a benefit to select groups of patients when compared with traditional second intent healing. 4 We postulate that surgeons who use these materials have developed these preferences described above from anecdotal or personal experiences as opposed to prospective data.…”

Comparing the application of various engineered xenografts for skin defects: A systematic review

“…Other dermal substitutes were used and included: Apligraf, Integra, PuraPly, AmnioFill, Epifix, Kerecis, and Puracol. 8,37,39,43,44 These dermal substitutes can expedite secondary healing and achieve better scar quality and satisfactory cosmetic results when compared to second-intention healing. 43,44 Integra with STSG showed higher graft take than Matriderm with STSG.…”

“…8,37,39,43,44 These dermal substitutes can expedite secondary healing and achieve better scar quality and satisfactory cosmetic results when compared to second-intention healing. 43,44 Integra with STSG showed higher graft take than Matriderm with STSG. 39 However, Matriderm is superior to Integra because it can be a one-stage procedure combined with NPWT.…”

Use of xenografts and allografts in scalp reconstruction

“…Puracol (Medline Industries, Mundelein, IL) is a 100% bovine-derived collagen matrix that has been used in scalp reconstruction [6]. In 11 patients following MOHs resection of dermatologic tumors, all patients achieved scalp closure with Puracol and weekly dressing changes, even in wounds occupying > 50% of the scalp with bone exposure [6]. They did not require bone chiseling.…”