Telle and Proskurowksi introduced restrained domination as a vertex partition problem in partial k-tress (Algorithms for vertex partitioning problems on partial k-trees, SIAM Journal on Discrete Mathematics 10(4) (1997), 529 -550). For a graph G(V , E), a restrained domination number is the minimum cardinality of a subset D of V such that for every vertex v ∈ D there is a vertex in D as well as in D adjacent to v. If D satisfies an additional condition that every vertex of V has a neighbor in D, then D is said to be a total restrained dominating set. Minimum cardinality of D is said to be total restrained domination number of graph G. In this paper we have obtained domination, restrained, total and total restrained domination number of some ladder graphs.