For any non-abelian group G, the non-commuting graph of G, Γ = Γ G , is graph with vertex set G\Z(G), where Z(G) is the set of elements of G that commute with every element of G and distinct non-central elements x and y of G are joined by an edge if and only if xy = yx. The non-commuting graph of a finite Moufang loop has been defined by Ahmadidelir. In this paper, we show that the multiple complete split-like graphs and the non-commuting graph of Chein loops of the form M (D 2n , 2) are perfect (but not chordal). Then, we show that the non-commuting graph of a non-abelian group G is split if and only if the non-commuting graph of the Moufang loop M (G, 2) is 3−split. Precisely, we show that the non-commuting graph of the Moufang loop M (G, 2), is 3−split if and only if G is isomorphic to a Frobenius group of order 2n, n is odd, whose Frobenius kernel is abelian of order n. Finally, we calculate the energy of generalized and multiple splite-like graphs, and discuss about the energy and also the number of spanning trees in the case of the non-commuting graph of Chein loops of the form M (D 2n , 2).