In this paper it is proved that anisotropic fractional maximal operator M α,σ , 0 ≤ α < |σ| is bounded on anisotropic generalized Morrey spaces M p,ϕ,σ , where |σ| = n i=1 σ i is the homogeneous dimension of R n . We find the conditions on the pair (ϕ 1 , ϕ 2 ) which ensure the Spanne-Guliyev type boundedness of the operator M α,σ from anisotropic generalized Morrey space M p,ϕ 1 ,σ to M q,ϕ 2 ,σ , 1 < p ≤ q < ∞, 1/p − 1/q = α/|σ|, and from the space M 1,ϕ 1 ,σ to the weak space W M q,ϕ 2 ,σ , 1 < q < ∞, 1 − 1/q = α/|σ|. We also find conditions on the ϕ which ensure the AdamsGuliyev type boundedness ofAs applications, we establish the boundedness of some Schödinger type operators on anisotropic generalized Morrey spaces related to certain nonnegative potentials belonging to the reverse Hölder class.