We study higher-order elliptic operators on one-dimensional ramified structures (networks). We introduce a general variational framework for fourth-order operators that allows us to study features of both hyperbolic and parabolic equations driven by this class of operators. We observe that they extend to the higher-order case and discuss well-posedness and conservation of energy of beam equations, along with regularizing properties of polyharmonic heat kernels. A noteworthy finding is the discovery of a new class of well-posed evolution equations with Wentzell-type boundary conditions.