“…In 2017, a team led by Peter de Keizer, a researcher specializing on aging at University Medical Center Utrecht in the Netherlands, described a cell-permeable peptide comprising part of FOXO4 that could disrupt this process 12 . By freeing p53 to exit the nucleus and engage apoptotic pathways in the cytoplasm of senescent cells, the therapy, which incorporated right-handed amino acids for added potency, helped counteract frailty, hair loss and renal dysfunction in mice.…”