Botulinum toxoid in the management of gustatory sweating (Frey’s syndrome) after superficial parotidectomy

Botulinum Toxin for the Treatment of Facial Flushing

“…[12][13][14][15] Botulinum has also been used to treat Frey's syndrome (gustatory sweating) and ''crocodile tears'' (gustatory epiphora). [16][17][18] Botulinum toxin works via inhibition of acetylcholine release at the presynaptical motor neuron. The temporary inhibition of nervous conduction allows for the relaxation of muscles that cause hyperdynamic lines.…”

Long-Term Efficacy and Quality of Life in the Treatment of Focal Hyperhidrosis with Botulinum Toxin A

“…In the treatment of forehead hyperhidrosis, botulinum toxin A has been shown to significantly reduce the amount of sweating for at least 5 months 3 . Botulinum toxin A has also been shown to be effective in treating focal hyperhidrosis associated with Frey's syndrome 26,27 …”

Botulinum toxin treatment for a compensatory hyperhidrosis subsequent to an upper thoracic sympathectomy

“…Consequently, the effects of botulinum toxin are temporary. 9 We observed the benecial effects of the injections were gradually reduced, but remained for 8 months.…”