2011
DOI: 10.3899/jrheum.101081
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Botulinum Toxin for Shoulder Pain: A Cochrane Systematic Review

Abstract: With evidence from few studies with small sample sizes and medium to high risk of bias, botulinum toxin type A injections decreased pain and improved shoulder function in patients with chronic shoulder pain due to spastic hemiplegia or arthritis.

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Cited by 28 publications
(29 citation statements)
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References 53 publications
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“…In a systematic review performed by Singh and Fitzgerald (2011), five RCTs in patients with HSP found that an intramuscular injection of BoNT/A significantly reduced pain at 3Y6 months and improved shoulder external rotation at 1 month. The work of Teasell, Foley, Pereira, Sequeira, and Miller (2012) concluded that botulinum toxin injected into the subscapularis muscle could reduce spastic shoulder pain and improve passive range of motion of the hemiplegic shoulder.…”
Section: Pharmacologic Therapiesmentioning
confidence: 98%
“…In a systematic review performed by Singh and Fitzgerald (2011), five RCTs in patients with HSP found that an intramuscular injection of BoNT/A significantly reduced pain at 3Y6 months and improved shoulder external rotation at 1 month. The work of Teasell, Foley, Pereira, Sequeira, and Miller (2012) concluded that botulinum toxin injected into the subscapularis muscle could reduce spastic shoulder pain and improve passive range of motion of the hemiplegic shoulder.…”
Section: Pharmacologic Therapiesmentioning
confidence: 98%
“…Анализ исследова-ний применения БТА при постинсультной боли в плече показал значительное и достоверное снижение боли. В предыдущем систематическом обзоре 2011 г. было также подтверждено, что БТA уменьшает боль и улучшает функцию плеча у пациентов, страдающих хронической болью в плече после спастической гемиплегии или артрита [60]. Однако авторы делают вывод, что для под-тверждения эффективности нейротоксина при данной патологии необходимы дополнительные широкомас-штабные многоцентровые РКИ, поскольку все исследова-ния проводились на небольшом количестве пациентов.…”
Section: особенности клинического проявления антиноцицептивного эффекunclassified
“…However, recent research has revealed likely additional antinociceptive properties of the toxin. 30 Botulinum toxin A provides another therapeutic option for clinicians to treat patients with shoulder pain at little additional risk to the patient. 26--28 Several studies have examined the potential beneficial effects of the toxin.…”
Section: Injectionsmentioning
confidence: 99%