Botulinum toxin for refractory vocal tics

Salloway, Stephen; Stewart, Celia; Israeli, Lisa; Morales, Ximena Ochoa; Rasmussen, Steven A.; Blitzer, Andrew; Brain, Mitchell F.

doi:10.1002/mds.870110627

Cited by 46 publications

(22 citation statements)

References 11 publications

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“…Several reports have described dramatic benefit from injection of botulinum toxin into the thyroarytenoid muscles [115,120,132]. Botulinum toxin improved not only the vocal tics but also the premonitory urge to tic.…”

Section: Malignant Vocal Ticsmentioning

confidence: 95%

Movement disorder emergencies

Poston

Frucht

2008

J Neurol

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Movement disorder emergencies include any movement disorder which evolves over hours to days, in which failure to appropriately diagnose and manage can result in patient morbidity or mortality. It is crucial that doctors recognize these emergencies with accuracy and speed by obtaining the proper history and by being familiar with the phenomenology of frequently encountered movements. These disorders will be discussed based on the most common associated involuntary movement, either parkinsonism, dystonia, chorea, tics or myoclonus, and, when available, review the workup and treatment options based on the current literature.

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Section: Malignant Vocal Ticsmentioning

confidence: 95%

Movement disorder emergencies

Poston

Frucht

2008

J Neurol

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“…Local injections of botulinum toxin can be considered when one or a few dystonic tics are present in patient's repertoire, such as holding of a sustained neck posture or sustained eye closure 36 , cervical tics associated with myelopathy 37 and laryngeal injections for severe vocal tics, including copralalia 38 .…”

Section: Tic-suppressing Drugsmentioning

confidence: 99%

Epidemiology of Tics

Ortiz¹,

Cornejo²,

Blazicevich³

2012

Epidemiology Insights

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“…Botulinum toxin (Salloway et al 1996), in injection, appears to have a limited role in the treatment of TD. It has been used for localized facial tics and vocal tics (because it appears to decrease the loudness).…”

Section: Other Pharmacologic Agents and Modalities Of Treatmentmentioning

confidence: 99%

An Overview of the Treatment of Tourette's Disorder and Tics

Párraga

Harris

Párraga

et al. 2010

Journal of Child and Adolescent Psychopharmacology

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Objective: The aim of this study was to review the efficacy of various treatments for Tourette's disorder (TD) and tics. Method: This study is a historical review of the treatment modalities prior to the advent of neuroleptics. A review of doubleblind and placebo-controlled clinical trials and open studies on the use of neuroleptics and selected reports was also carried out. Results: The literature review reveals that the treatment of TD and tics has evolved from an early history of marginally effective approaches to the advent of neuroleptics, which started a new era in TD and tic treatment, with a significantly broader range of effectiveness. Conclusions: Although progress has been made, the literature review nevertheless reveals a great deal of confusion as related to the clinical heterogeneity of TD and tics, differences in populations, medication-dose combinations, and outcomes. However, a role for a limited number of pharmacologic agents, combined with psychosocial approaches, has been identified. There is a need for studies in larger, diagnostically homogenous samples and for the use of more sophisticated methodology, to identify intelligible models that would allow the development of more effective treatment approaches.

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Botulinum toxin for refractory vocal tics

Cited by 46 publications

References 11 publications

Movement disorder emergencies

Movement disorder emergencies

Epidemiology of Tics

An Overview of the Treatment of Tourette's Disorder and Tics

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