Botulinum toxin-A injection into the anterior belly of the digastric muscle for the prevention of post-operative open bite in class II malocclusions: a case report and literature review

Kang, Yei-Jin; Kuen, Bong; Choi, Dong Soon; Jang, In San; Kim, Seong‐Gon

doi:10.1186/s40902-019-0201-9

Cited by 10 publications

(4 citation statements)

References 29 publications

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“…Clinical applications of BTX-A In three of the included studies [10,18,27], patients received BTX-A injection into the ABDM muscle as an adjunctive therapy for orthognathic and trauma surgery, in order to prevent postoperative relapse. It is known that skeletal stability following mandibular advancement is a controversial topic in the literature, with various factors being implicated in postoperative relapse [28].…”

Section: Discussionmentioning

confidence: 99%

“…As BTX-A injections induce muscular weakness, some authors showed that BTX-A injection into the ABDM can correct an open bite caused by a bilateral mandibular angle fracture [10]. A single dose of BTX-A injection into the ABDM can be a useful method in preventing surgical relapse in patients with deep-bite and open-bite malocclusion, treated with orthognathic surgery [17,18].…”

Section: Introductionmentioning

confidence: 99%

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Botulinum Toxin Injection into the Digastric Muscle: Current Clinical Use and a Report of Five Cases

Ban,

Roman,

Bran

et al. 2023

Biomedicines

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The present research aimed to review the clinical applications of botulinum toxin-A (BTX-A) injection into the anterior belly of the digastric muscle (ABDM) and to highlight the potential role of the BTX-A injection into ABDM in preventing postsurgical relapse. Five Class II malocclusion patients who underwent orthognathic surgery received BTX-A injections into both ABDM for the prevention of postoperative relapse. The relapse was evaluated using lateral cephalometric radiographs by comparing the postoperative cephalometric analyses at two different time points, postoperatively at 2 weeks (T1), and long-term, at 9 months after the surgical intervention (T2). The results demonstrated no significant differences between T2 and T1 for the Selle-Nasion-point A (SNA) angle, Selle-Nasion-point B (SNB) angle, point A-Nasion-point B (ANB) angle, mandibular length, and sagittal mandibular position. The patients exhibited stable occlusion without any signs of relapse after the surgery. A single BTX-A injection into the ABDM can effectively prevent postoperative relapse in Class II malocclusion patients, following orthognathic surgery. From a clinical perspective, in case of optimal dosage and procedure, BTX-A injection could be considered as the primary option for the prevention of postsurgical relapse for Class II malocclusion patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Botulinum Toxin Injection into the Digastric Muscle: Current Clinical Use and a Report of Five Cases

Ban,

Roman,

Bran

et al. 2023

Biomedicines

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“…In addition to its aesthetic function, the toxin can also be used functionally in other muscles to reduce muscle tension in the postoperative phase, prevent fracture or displacement of the fixation material, 6 and reduce the likelihood of recurrences caused by muscle hyperactivity. 7 , 8 …”

Section: Discussionmentioning

confidence: 99%

Use of non-surgical aesthetic refinement after orthognathic surgery: Case studies

Grillo

Borba

Lima

et al. 2022

Journal of Taibah University Medical Sciences

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“…Osteofixation was achieved by absorbable PLLA, which demonstrated predictable skeletal stability compared to that of titanium plating systems [14]. Immediately after the orthognathic procedure, we injected routine dosage of botulinum toxin into the masseter muscles bilaterally to decrease the muscular force [15]. In the surgical change, point B was significantly moved superiorly in the CA group but not in the SFA group, although maxillary impaction had been performed.…”

Section: Discussionmentioning

confidence: 99%

Surgery-first approach reduces the overall treatment time without damaging long-term stability in the skeletal class III correction: a preliminary study

Park

Kwon

Kang

et al. 2021

Maxillofac Plast Reconstr Surg

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Background Compared to the conventional approach, including preoperative orthodontic preparation, the so-called surgery-first approach (SFA) seems to reduce the overall treatment time in the correction of skeletal class III dentofacial deformity. However, there have been controversies about postoperative skeletal stability with SFA. Therefore, we investigated the long-term stability and the overall treatment time after maxillomandibular surgery for skeletal class III correction with or without preoperative orthodontic preparation. Methods This retrospective study included eight patients who underwent maxillomandibular surgery for class III correction with the SFA (SFA group) and 20 patients who underwent the conventional approach (CA group). A comparative study of the change in the maxillary and mandibular position on preoperative (T1), 1-day (T2), 6-month (T3), and 2-year (T4) postoperative lateral cephalograms. We calculated the overall treatment time for each group. Results At the presurgical stage (T1), there was no bias in the skeletal features between the two groups. In the surgical change from T1 to T2, the mandible (point B) of the CA group was significantly moved superiorly. Short-term changes from T2 to T3 revealed that the mandible moved forward in both groups, whereas the maxillary position showed no significant changes. Long-term changes from T3 to T4 demonstrated that none of the measured parameters showed any significant differences. Finally, the average of overall treatment time was 15.1 months in the SFA group and 26.0 months in the CA group. Conclusions These findings suggest that SFA in bimaxillary orthognathic surgery for skeletal class III correction leads to predictable long-term skeletal stability, similar to surgery with CA. Furthermore, SFA reduced the overall treatment time compared to CA.

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Botulinum toxin-A injection into the anterior belly of the digastric muscle for the prevention of post-operative open bite in class II malocclusions: a case report and literature review

Cited by 10 publications

References 29 publications

Botulinum Toxin Injection into the Digastric Muscle: Current Clinical Use and a Report of Five Cases

Botulinum Toxin Injection into the Digastric Muscle: Current Clinical Use and a Report of Five Cases

Use of non-surgical aesthetic refinement after orthognathic surgery: Case studies

Surgery-first approach reduces the overall treatment time without damaging long-term stability in the skeletal class III correction: a preliminary study

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