Botryoid rhabdomyosarcoma of the biliary tract in children: a unique case report

Zampieri, Nicola; Camoglio, Francesco Saverio; Corroppolo, Michele; Cecchetto, Mariangela; Ornis, Sara; Ottolenghi, A.

doi:10.1111/j.1365-2354.2006.00683.x

Cited by 31 publications

(20 citation statements)

References 18 publications

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“…Median age at presentation is 3 years, but it should be included in the differential diagnosis of an infant presenting with jaundice and a mass in the porta hepatis. Other diagnostic possibilities include undifferentiated sarcoma of the liver, pancreateoblastoma, papillary cystic tumor of the pancreas, metastatic lesions and more rarely, hepatoblastoma [50,51] . Additionally, a RMS in this location can mimic the radiological appearance of a choledochal cyst because of its combined cystic and solid component [52] .…”

Section: Biliary Tract Rhabdomyosarcomamentioning

confidence: 99%

Differential diagnosis and management of liver tumors in infants

Fernández-Pineda

Cabello-Laureano

2014

WJH

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During the first year of life, most of the liver neoplasms are benign in origin, but some of these histologically benign lesions may be challenging in their management. Although most hepatic hemangiomas can be safely observed until involution is documented, some patients will need treatment due to progressive hepatomegaly, hypothyroidism and/or cardiac failure. Large mesenchymal hamartomas may require extensive hepatic resection and an appropriate surgical plan is critical to obtain good results. For malignant neoplasms such as hepatoblastoma, complete surgical resection is the mainstay of curative therapy. The decision about whether to perform an upfront or delayed resection of a primary liver malignant tumor is based on many considerations, including the ease of resection, surgical expertise, tumor histology and stage, and the likely chemosensitivity of the tumor. This article reviews the initial management of the more common hepatic tumors of infancy, focusing on the differential diagnosis and treatment options.

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Section: Biliary Tract Rhabdomyosarcomamentioning

confidence: 99%

Differential diagnosis and management of liver tumors in infants

Fernández-Pineda

Cabello-Laureano

2014

WJH

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“…It is a disease of young children (average age 3 years) with a slight male preponderance. 3,4 This tumor that mainly arises from the CBD may occur in any part of the biliary tree, resulting in symptoms of obstructive jaundice which is observed in 60%-80% of the cases. Clinical presentation may include other symptoms such as abdominal pain, emesis, fever, acholic stools, and decreased appetite.…”

Section: Discussionmentioning

confidence: 99%

“…1 Because of the scarcity of this disease, the majority of the pediatric literature consists of isolated case reports. 2,3 Here, we present a case of a male child with embryonal RMS originating in the common bile duct.…”

Section: Introductionmentioning

confidence: 99%

Rhabdomyosarcoma of the biliary tract: a case report

Kouadir

Mazghi

Hassouni

2017

Int J Contemp Pediatr

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Rhabdomyosarcoma (RMS) of the biliary tract is a rare tumor that commonly arises from the common bile duct. The most common clinical symptoms are obstructive jaundice and abdominal pain. Although diagnosis is often difficult and is frequently made during surgery, diagnostic imaging techniques including ultrasound, computerized tomography scan, and magnetic resonance cholangiopancreatography remain useful in the diagnosis and evaluation of biliary tree anatomy. In order to improve prognosis, different rhabdomyosarcoma study groups have adopted multidisciplinary treatment approach. Herein we describe a case of three-year-old child with Embryonal rhabdomyosarcoma originating in the common bile duct who was treated with surgery, chemotherapy according to European soft tissue sarcoma group (EpSSG) protocol and adjuvant postoperative intensity modulated radiotherapy to surgical bed with 6 MV photons to a dose of 41, 4Gy in 23 fractions. One year and a half after the end of therapy, the patient is still disease free. Although Rhabdomyosarcoma of the biliary tract is a rare tumor, it should be considered in the differential diagnosis of patients who have obstructive jaundice and a cystic mass within the common bile duct. Once believed to be an incurable disease, the prognosis of patients with biliary rhabdomyosarcoma has improved with a multidisciplinary treatment approach.

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“…Although it is the most common biliary tumor in children, BRMS comprises only about 1% of all rhabdomyosarcomas [1][2][3] . BRMS usually arises in the CBD, but may originate from anywhere along the biliary tree.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic and therapeutic role of endoscopic retrograde cholangiopancreatography in biliary rhabdomyosarcoma

Himes

Raijman²,

Finegold³

et al. 2008

WJG

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Biliary rhabdomyosarcoma (BRMS) is an uncommon childhood malignancy which has been managed surgically. We present a case of a 3-year-old boy with BRMS, in whom endoscopic retrograde cholangiopancreatography (ERCP) was successfully used both diagnostically and therapeutically, thus obviating the need for surgery and its attendant risks of morbidity and mortality. We conclude that ERCP is an effective alternative to surgery for BRMS in some patients.

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Botryoid rhabdomyosarcoma of the biliary tract in children: a unique case report

Cited by 31 publications

References 18 publications

Differential diagnosis and management of liver tumors in infants

Differential diagnosis and management of liver tumors in infants

Rhabdomyosarcoma of the biliary tract: a case report

Diagnostic and therapeutic role of endoscopic retrograde cholangiopancreatography in biliary rhabdomyosarcoma

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