Botox rechallenge—An additional tool in the management of an incompletely emptying bladder and inadequate overactive symptom control following sacral neuromodulation

Abstract

Two female patients aged 70 and 72 with video-urodynamics-confirmed detrusor overactivity and detrusor underactivity (DO-DU) were treated. Patients were refractory to medical therapies and had previously failed intravesical botulinum toxin type A (BoNT-A) at other centers secondary to urinary retention and difficulty with selfcatheterization.