Bothrops alternatus snake venom induces apoptosis of skeletal muscle cells in a rabbit model

Abstract

Bothrops alternatus snake venom induces apoptosis of skeletal muscle cells in a rabbit model [O veneno da serpente Bothrops alternatus induz apoptose nas células musculares de coelhos]

Effect of Bitis gabonica and Dendroaspis angusticeps snake venoms on apoptosis-related genes in human thymic epithelial cells

“…The apoptotic potential of Bothrops atrox LAAOs has been correlated with increased levels of caspase-3 and caspase-9 in HL60, Jurkat, PC12 and B16F10 cell lines [ 85 ]. In a communication disclosed by Santos et al [ 86 ] caspase-3 mediated apoptosis of rabbit skeletal muscle myocytes has been attributed to envenomation with Bothrops alternatus . Tavares et al [ 87 ] have shown that Calloselasma rhodostoma SV-LAAOs might contribute to cytotoxic cellular events by the activation of caspase-3 and caspase-8 in hyperproliferative myeloid cells.…”