Both muscle mass and muscle strength are inversely associated with depressive symptoms in an elderly Chinese population

Wang, Hongmei; Yu, Bin; Meng, Guang; Liu, Fangfang; Guo, Qi; Wang, Jiazhong; Du, Huanmin; Zhang, Wen; Shen, Suxing; Han, Peipei; Dong, Renwei; Wang, Xiuyang; Ma, Yixuan; Chen, Xin; Niu, Kaijun

doi:10.1002/gps.4522

Cited by 29 publications

(29 citation statements)

References 28 publications

(47 reference statements)

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“…So far, an inverse association between cardiorespiratory fitness and risk of depression have been well-established among young ( 14 ) and middle-aged adults ( 15 ; 16 ) . Similarly, previous studies also reported an association between muscular strength and depression risk among the elderly population (17)(18)(19) . However, to our knowledge, there have been no reports yet on whether muscle strength has a significant association with depression at younger ages.…”

Section: Introductionsupporting

confidence: 67%

“…For subject's characteristics, continuous variables were compared using analysis of variance (ANOVA), and categorical variables were compared by using chi-square tests. Currently, the relationship between higher handgrip strength (indicator of overall muscle strength), and lower risk of depressive symptoms is already widely accepted (17)(18)(19) . However, this relationship had not been previously confirmed among younger adults.…”

Section: Discussionmentioning

confidence: 99%

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Association between Muscular Strength and Depressive Symptoms among Chinese Nursing Freshmen—A Cross-Sectional Study

Ren

Guo

Cao

et al. 2019

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Increased physical activity level is related to lower risk of depressive symptoms, and an inverse association between muscular strength and risk of depressive symptoms among the elderly population. However, the association among younger adults is unclear. The aim of this study was to examine the association between muscle strength, using handgrip strength as a representative of skeletal muscle strength, and the risk of depressive symptoms among Chinese female college freshman. A cross-sectional study was conducted among 867 participants aged between 16-23 years. Handgrip strength was measured with a handheld digital Smedley dynamometer, and depressive symptoms were evaluated using the 20-item Zung self-rating depression scale (SDS) with 3 cut-off points to indicate elevated depressive symptoms. We found that 10.7% of participants (17.2% or 29.2%) were classified as having moderate to severe depressive symptoms using 50 as the cut-off point. After adjusting for these potential confounders, the adjusted odds ratios for moderate-to-severe depressive symptoms across tertile of relative handgrip strength were 1.00 (reference) for tertile 1, 0.61 (95% CI: 0.35, 1.04) for tertile 2, and 0.53 (95% CI: 0.39, 0.94) for tertile 3 (P for trend: 0.024). The significant associations remained when other cut-off points (SDS 48 or 45) were used. Interactions between the handgrip strength and potential confounders for depressive symptoms in the final models were insignificant. This study showed that handgrip strength is inversely and independently related to the risk of depressive symptoms among Chinese female college freshman. These results can help with the development of an effective intervention strategy against depression. For future research, it is important to explore the causality of the effects of handgrip strength on the depressive symptoms by intervention study.

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Section: Introductionsupporting

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Association between Muscular Strength and Depressive Symptoms among Chinese Nursing Freshmen—A Cross-Sectional Study

Ren

Guo

Cao

et al. 2019

Preprint

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“… 19 Reduction in grip strength was also reported to be associated with a higher risk of depressive symptoms. 9 , 20 In a recent cross-sectional survey, Wu et al 10 identified that both muscle mass and muscle strength were inversely associated with depressive symptoms in elderly Chinese individuals. Additionally, sarcopenic obesity was demonstrated to be positively associated with depressive symptoms 21 and lower indicators of psychological health, including perceived stress and suicidal ideation.…”

Section: Discussionmentioning

confidence: 99%

“… 8 A prospective cohort study reported that lower handgrip strength (HS) was associated with depressive symptoms in Japanese individuals. 9 Additionally, Wu et al 10 recently identified that depressive symptoms are inversely associated with both muscle mass and muscle strength in elderly Chinese individuals. However, some findings have been inconsistent between studies; the data from the 2010–2011 Korean National Health and Nutrition Examination Survey reported that depression was not associated with sarcopenia.…”

Section: Introductionmentioning

confidence: 99%

Association between depressive symptoms and sarcopenia in older Chinese community-dwelling individuals

Wang

Hai

Liu

et al. 2018

CIA

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PurposeThe aim of this study was to assess the prevalence of sarcopenia and depressive symptoms and estimate the association between them in elderly Chinese community-dwelling individuals.Patients and methodsA total of 948 elderly Chinese community-dwelling individuals were recruited through leaflets and posters from three communities in Chengdu, and 865 participants were analyzed in this cross-sectional study. Muscle mass was measured using the bioimpedance analysis, handgrip strength was measured with a handheld dynamometer, and physical performance was assessed via usual gait speed on a 6 m course. Sarcopenia was defined according to the recommended diagnostic algorithm of the Asia Working Group for Sarcopenia (AWGS). Depressive symptoms were assessed using the Chinese version of 15-item Geriatric Depression Scale (GDS-15) with a score of ≥5 indicative of the presence of depressive symptoms.ResultsA total of 865 participants were included in the analysis. The participants had a mean age of 68.68±6.46 years. Sixty-one (7.1%) participants and 71 (8.2%) participants were identified as having sarcopenia and depressive symptoms, respectively. After adjusting for age, sex, and other potential confounders, sarcopenia was found to be significantly associated with depressive symptoms (odds ratio [OR]: 2.23, 95% CI 1.06–4.92).ConclusionThe prevalence rates of sarcopenia and depressive symptoms were 7.1 and 8.2%, respectively, in elderly Chinese community-dwelling individuals, and sarcopenia was significantly associated with depressive symptoms.

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“…The reported factors of depression in old age include genetic susceptibility, chronic diseases, disability, pain, frustration with limitations in activities of daily living, personality trait, adverse life events (widowhood, separation, divorce, bereavement, poverty, social isolation) and lack of adequate social support (Levav & Rutz, 2002). Even lower muscle mass, lower muscle strength and vitamin D de ciency contribute to late-life depression (Wu et al, 2017;Okereke & Singh, 2016). These studies on risk factors of elderly depression have mainly been reported in the western countries, but seldom in Chinese population.…”

Section: Introductionmentioning

confidence: 99%

Risk factors associated with depressive symptoms in older people based on comprehensive geriatric assessment in Chongqing China

Duan¹,

Wang²,

Yu³

et al. 2020

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Background As a common geriatric syndrome in the elderly, depression is often associated with many risk factors. The occurrence of depression shows cultural and geographical differences. Aims To explore the prevalence of depression and risk factors associated with depressive symptoms in the elderly peoples in Chongqing, China. Methods A cross-sectional study based on comprehensive geriatric assessment questionnaire was conducted among 925 participants aged 60 years or older. Depressive symptoms were evaluated using the 30-item Geriatric Depression Scale. Risk factors related to depression were evaluated, including gender, age, education, marital status, type of work, living status, chronic diseases, disability, self-reported health, smoking, alcohol, exercise, and current working status. Results 219 (23.67%) of elderly participants suffered from depressive symptoms. Unmarried status, older age, poor self-reported health, disability, irregular exercise and chronic diseases were significantly associated with depressive symptoms in the elderly (P < 0.05). Multivariate logistic regression analysis showed that independent predictors of geriatric depression included unmarried status, poor self-reported health and disability. Conclusions The prevalence of depressive symptoms is high in Chinese old people. Risk factors of depression are mainly social support- and lifestyle- associated. Evaluation of risk factors is a vital strategy for preventing depression and taking interventions.

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Both muscle mass and muscle strength are inversely associated with depressive symptoms in an elderly Chinese population

Abstract: Both muscle mass and muscle strength are inversely associated with depressive symptoms in elderly Chinese. These findings may provide novel insights linking skeletal muscle and depressive symptoms. Copyright © 2016 John Wiley & Sons, Ltd.

Cited by 29 publications

References 28 publications

Association between Muscular Strength and Depressive Symptoms among Chinese Nursing Freshmen—A Cross-Sectional Study

Association between Muscular Strength and Depressive Symptoms among Chinese Nursing Freshmen—A Cross-Sectional Study

Association between depressive symptoms and sarcopenia in older Chinese community-dwelling individuals

Risk factors associated with depressive symptoms in older people based on comprehensive geriatric assessment in Chongqing China

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