Boosting Cosmeceutical Peptides: Coupling Imidazolium-Based Ionic Liquids to Pentapeptide-4 Originates New Leads with Antimicrobial and Collagenesis-Inducing Activities

Abstract

As life expectancy increases, diseases causing chronic wound infections become more prevalent. Diabetes, peripheral vascular diseases, and bedridden patients are often associated with non-healing wounds that become infected, resulting in high morbidity and mortality.

Liposome Encapsulation of the Palmitoyl–KTTKS Peptide: Structural and Functional Characterization

“…The intensity of the stain is evident in the positive controls (ascorbic acid 1 mM and free pal-KTTKS, Figure 4 B,G and H, respectively) with a pattern of coloration similar to that observed by other groups in similar experiments [ 18 , 24 ] and in liposome-encapsulated peptide treatments ( Figure 4 C–F,I–L). A similar result regarding collagen production induced by pal-KTTKS conjugated with ionic liquids was observed by Gomes et al [ 31 ].…”