Bone tumors: osteosarcoma and Ewingʼs sarcoma

Abstract

This report will provide an overview of the current treatment options and long-term complications in primary malignant bone tumors for the pediatrician caring for a child with these problems.

Over 10-year follow-up of functional outcome in patients with bone tumors reconstructed using distraction osteogenesis

“…Dramatic improvements in the survival rate of patients with musculoskeletal tumors and in the successful salvage of limbs have occurred as a result of progress in chemotherapy, radiological evaluation, and surgical technique, as well as in materials and implant technology, thereby making limb salvage an important alternative for the restoration of function [1][2][3]. Reconstruction of bone defects following en bloc resection of malignant or aggressive benign bone tumors is one of the major challenges in orthopedic surgery.…”

Ewing’s Sarcoma of Mandible: A Very Rare Disease and Review of Indian Literature

“…On examination there was a left mandbular swelling of size 7×4 cm [2], firm to hard in consistency with few places of cystic consistency, local temp. was raised and swelling was tender.…”

“…Males are affected more commonly than females and it is more common in white population. Clinically, this tumor has an aggressive behavior characterized by rapid growth and high probability of micrometastasis at the time of diagnosis [2].…”

Cytokine Induced Killer cells are effective against sarcoma cancer stem cells spared by chemotherapy and target therapy.

“…Undifferentiated pleomorphic sarcoma (UPS) is among the most frequent STS in adults (10-20%), 1,2 osteosarcoma (OS) is the most common primary bone tumor occurring predominantly in adolescents and young adults. 3 …”