Bone tissue regeneration implanting matrix obtained by recombinant DNA techniques

Coletta, D.J.; Ibáñez‐Fonseca, Arturo; Missana, Liliana Raquel; Bumaguin, G.E.; Vitelli, Ezequiel J.; Garbino, F.; Zabalza, Facundo; Amavet, C.; Aimone, M.; Jammal, María Victoria; Alonso, Matilde; Rodríguez‐Cabello, José Carlos; Feldman, Sara

doi:10.1016/j.bone.2015.12.044

Cited by 1 publication

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“…On the other hand, bone defects have been also treated with bioactive and biodegradable ELR-based hydrogels formed with an ELR fused to the bone morphogenetic protein-2 (BMP-2), which is a very powerful osteogenic factor. In this case, fully repaired defects were found after 3 months, showing the good performance of the hydrogels to promote this regeneration [108].…”

Section: Elrs For Enhancing Implant Vascularizationmentioning

confidence: 60%

Trends in the design and use of elastin-like recombinamers as biomaterials

et al. 2019

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Elastin-like recombinamers (ELRs), which derive from one of the repetitive domains found in natural elastin, have been intensively studied in the last few years from several points of view. In this mini review, we discuss all the recent works related to the investigation of ELRs, starting with those that define these polypeptides as model intrinsically disordered proteins or regions (IDPs or IDRs) and its relevance for some biomedical applications. Furthermore, we summarize the current knowledge on the development of drug, vaccine and gene delivery systems based on ELRs, while also emphasizing the multiple tissue engineering approaches involving their use. Finally, we show different studies that explore applications in other fields, and several examples that 2 describe biomaterial blends in which ELRs have a key role. This review aims to give an overview of the recent advances regarding ELRs and to encourage further investigation of their properties and applications.

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Section: Elrs For Enhancing Implant Vascularizationmentioning

confidence: 60%