Bone scintigraphy as a diagnostic method in unilateral hyperactivity of the mandibular condyles: a review and meta-analysis of the literature

Unilateral condylar hyperplasia recurrence after orthognathic surgery: a case report

“…Literature based on control studies indicate that normal individuals or patients without progressive facial asymmetry show a difference in radiotracer uptake values between the left and right condylar regions less than 10%, whereas a difference greater than 10% is strongly suggestive of active UCH [12]. Nevertheless, a systematic review of the literature by Saridin et al reported a large variability between studies from different centers performing SPECT scan [5]. Besides the 10% cut-off value reported by Saridin and colleagues, it is the Authors' opinion that every Nuclear Medicine center should define their own cut-off value based on affected patients and a control group.…”

“…Diagnosis of UCH depends on an exhaustive anamnesis and clinical examination associated to an accurate imaging study. In this specific clinical setting, the diagnostic gold standard is represented by clinical diagnosis [5].…”

The Use of 99mTc-MDP Bone Scanning to Assess Facial Bone Growth

“…The ability to predict the cessation of facial bone growth before surgery is crucial in patients with mandibular prognathism, as well as in patients with unilateral condylar hyperactivity (1,2). Various imaging techniques such as hand and wrist radiographs, cephalograms, and 99m Tc-MDP bone scintigraphy are currently used to determine when facial bone growth has stopped, so that surgery can be most effective.…”

Reconstructive surgery of the temporomandibular joint

“…La cintigrafía ósea usando SPECT (single photon emission computed tomography) es el mejor método porque analiza cuantitativamente calculando las diferencias de percentil entre el cóndilo derecho e izquierdo. Una diferencia porcentual hasta de 10% se considera normal 13 . No obstante la ausencia de un gold standard para el diagnóstico de HC, el examen clínico es fundamental, ya que un cóndilo inflamado o en remodelación por sobrecarga puede aparecer con una mayor actividad cintigráfica, lo que constituye un falso positivo.…”