Bone resorption responses to potassium-enriched high-calcium skim milk

Green, J Hilary; Walmsley, T A; Richards, Jill; Bunning, Richard

doi:10.1016/s8756-3282(00)80154-4

Cited by 1 publication

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“…One of the most important methods is to dope different elements into the material to change its structure and properties, such as, K, Na, Mg, Zn, Sr, etc. [9][10][11][12] These doped elements exhibit no toxicity and no harm to the physical environment during the degradation process of CPP; additionally, they can play a significant roles in bone metabolism, growth, and nourishment absorption. 9,[13][14][15] The goal of this research was to explore the impact of doping different elements (K, Na, Mg, Zn, Sr) with various ion radius and electric charges into CPP's crystal structure (KCPP, NCPP, MCPP, ZCPP, SCPP).…”

Section: Introductionmentioning

confidence: 99%

“…As a result, optimizing the degradability and mineralization abilities of CPP and consequently promoting its biological function are challenges for further research. One of the most important methods is to dope different elements into the material to change its structure and properties, such as, K, Na, Mg, Zn, Sr, etc 9–12. These doped elements exhibit no toxicity and no harm to the physical environment during the degradation process of CPP; additionally, they can play a significant roles in bone metabolism, growth, and nourishment absorption 9, 13–15…”

Section: Introductionmentioning

confidence: 99%

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The study on the degradation and mineralization mechanism of ion‐doped calcium polyphosphate in vitro

et al. 2008

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Doping with different trace elements can significantly change the original degradability, mineralization, and biological properties of bone repair material. According to the fundamental research on prepared calcium polyphosphate (CPP) as a bone repair material by our group, this article began further exploration on the effect of doping different trace elements (K, Na, Mg, Zn, Sr) into CPP on its degradability and mineralization soaking in simulated body fluids. The results indicated that doped elements significantly changed the lattice parameters and cell volume of crystal, resulted in different types of crystal defect and surface charge distribution, and consequently changed the original degradability and mineralization of CPP. The conclusion is that doped ions with relatively smaller ionic radius and equivalent positive charge compared with Ca(2+) can greatly promote the degradability and mineralization of CPP, whereas doped ions with equivalent ionic radius and diverse positive charges compared with Ca(2+) provide less contribution on promoting the degradability and mineralization or even counteract.

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