Bone Preservation in Dehiscence-Type Defects Using Composite Biphasic Calcium Sulfate Plus Biphasic Hydroxyapatite/β-Tricalcium Phosphate Graft

Machtei, Eli E.; Rozitsky, Doron; Zigdon‐Giladi, Hadar; Levin, Liran

doi:10.1097/id.0b013e3182a62748

Cited by 6 publications

(4 citation statements)

References 27 publications

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“…This combination also displays good initial volume stability and strength . A previous canine study published by our group demonstrated its efficacy in dehiscence type extraction defects . Furthermore, a human clinical trial found superior results when compared to natural healing of extraction sockets in terms of horizontal dimensional changes after 4 months of healing .…”

Section: Introductionmentioning

confidence: 99%

“…10 A previous canine study published by our group demonstrated its efficacy in dehiscence type extraction defects. 11 Furthermore, a human clinical trial found superior results when compared to natural healing of extraction sockets in terms of horizontal dimensional changes after 4 months of healing. 12 De Rosi and colleagues 13 in a systematic review and meta-analysis of histomorphometric results with various grafting materials for socket preservation, reported a large variation in the amount of new bone formation between the various grafting materials, however none were shown to be statistically superior over the other.…”

Section: Introductionmentioning

confidence: 99%

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Prospective randomized controlled clinical trial to compare hard tissue changes following socket preservation using alloplasts, xenografts vs no grafting: Clinical and histological findings

Machtei

Mayer

Horwitz

et al. 2018

Clin Implant Dent Rel Res

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Purpose To compare dimensional changes and bone quality of two different grafting materials used for socket preservation. Materials and Methods Thirty‐three patients requiring extraction were recruited and randomly assigned to receive: biphasic calcium sulfate/ hydroxyapatite (BCS/HA); bovine derived xenograft (BDX) or no grafting (Control). Ridge width (at −3 and −6 mm) and vertical distance from a stent were measured at the time of extraction/grafting. Measurements were repeated at reentry and core biopsies were harvested. Results Baseline vertical distance for the BDX, C and BCS/HA groups were 7.45 ± 3.1, 7.69 ± 4.2, and 6.75 ± 3.5 mm, respectively (P = .830). Post‐op, C group had greater vertical loss (1.71 ± 0.4 mm) compared to BCS/HA (0.65 ± 0.5) and BDX (0.25 ± 0.2 mm), P = .059. Mean baseline width at −3 mm was 8.69 ± 1.1 mm, 8.31 ± 1.4 mm, and 9.0 ± 1.1 mm, respectively (P = .509). Post‐op, this width was reduced by 2.96 ± 0.3 mm (C), 1.56 ± 0.4 mm (BDX), and 0.5 ± 0.4 mm (BCS/HA), P = .001. Mean ridge width at −6 mm for the C (6.5 ± 1.7 mm) was significantly smaller than BCS/HA (7.95 ± 2.8 mm) and BDX (8.85 ± 1.9 mm), P = .043. Histologically, the BDX group had greater residual scaffold material and less vital bone compared to the BCS/HA group. Pain scores were relatively low for all groups. Conclusions BCS/HA may be used for socket preservation with similar or better results compared to BDX. The significance of greater residual scaffold found in the BDX group is yet to be determined.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prospective randomized controlled clinical trial to compare hard tissue changes following socket preservation using alloplasts, xenografts vs no grafting: Clinical and histological findings

Machtei

Mayer

Horwitz

et al. 2018

Clin Implant Dent Rel Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…The results showed that PGA: TMC membranes protected DFDB‐filled defects and yielded a greater amount of bone regeneration than the other two groups 127 . Machtei et al 128 demonstrated the bone‐enhancing effects of BCP/BCS grafts in split extraction socket defects 128 . In the study of Shafieian et al, 129 cylindrical penetrating defects were drilled in the mandibular plates of five mongrel dogs and were filled randomly with four different materials.…”

Section: Implantation Defect Models (Include Alveolar Ridge Expansion...mentioning

confidence: 99%

“…127 Machtei et al 128 demonstrated the bone-enhancing effects of BCP/BCS grafts in split extraction socket defects. 128 In the study of Shafieian et al, 129 cylindrical penetrating defects were drilled in the mandibular plates of five mongrel dogs and were filled randomly with four different materials. The results showed that PRP-assisted hADSCs generated bone tissue regeneration in canine alveolar bone defects.…”

Section: Canine (Dog) Modelmentioning

confidence: 99%

Oral hard tissue defect models for evaluating the regenerative efficacy of implant materials

Sun

Heng

Zhang

2023

MedComm – Biomaterials and Applications

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Oral hard tissue defects are common concomitant symptoms of oral diseases, which have poor prognosis and often exert detrimental effects on the physical and mental health of patients. Implant materials can accelerate the regeneration of oral hard tissue defects (such as periodontal defects, alveolar bone defects, maxilla bone defects, mandible bone defects, alveolar ridge expansion, and site preservation), but their regenerative efficacy and biocompatibility need to be preclinically validated in vivo with animal‐based oral hard tissue defect models. The choice of oral hard tissue defect model depends on the regenerative effect and intended application of the tested implant material. At the same time, factors that need to be considered include techniques for constructing the particular defect model, the scaffold/graft material used, the availability of animal model evaluation techniques and instrumentation, as well as costs and time constraints. In this article, we summarize the common oral hard tissue defect models in various animal species (such as periodontal model, jaw defect model, and implantation defect model) that can be used to evaluate the regenerative efficacy and biocompatibility of implant materials.

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Performance of an alloplastic material versus a mineralized allograft in alveolar ridge preservation: Clinical, micro-CT and histological analyses

Pripatnanont

Boonsri

Monmaturapoj

2022

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathol

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Bone Preservation in Dehiscence-Type Defects Using Composite Biphasic Calcium Sulfate Plus Biphasic Hydroxyapatite/β-Tricalcium Phosphate Graft

Abstract: This study demonstrates the efficacy of BCP/BCS graft for bone augmentation in dehiscence-type extraction socket defect.

Cited by 6 publications

References 27 publications

Prospective randomized controlled clinical trial to compare hard tissue changes following socket preservation using alloplasts, xenografts vs no grafting: Clinical and histological findings

Prospective randomized controlled clinical trial to compare hard tissue changes following socket preservation using alloplasts, xenografts vs no grafting: Clinical and histological findings

Oral hard tissue defect models for evaluating the regenerative efficacy of implant materials

Performance of an alloplastic material versus a mineralized allograft in alveolar ridge preservation: Clinical, micro-CT and histological analyses

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