Bone-on-a-chip simulating bone metastasis in osteoporosis
Sunghan Lee,
Young Gyun Kim,
Hyo-Il Jung
et al.
Abstract:Osteoporosis is the most common bone disorder, which is a highly dangerous condition that can promote bone metastases. As the current treatment for osteoporosis involves long-term medication therapy and a cure for bone metastasis is not known, ongoing efforts are required for drug development for osteoporosis. Animal experiments, traditionally used for drug development, raise ethical concerns and are expensive and time-consuming. Organ-on-a-chip technology is being developed as a tool to supplement such animal… Show more
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