Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis

Pulmonary function, functional capacity and quality of life in adults with cystic fibrosis

“…In children and adolescents, Donadio et al found an association between the physical domain of the CFQ-R and the 6MWT. 21 In our study, maybe because of the small sample size, there was no association between the CFQ scores and the 6MWT. Therefore, our results suggest that the pulmonary function may reflect the overall disease severity better than the functional capacity, and that the exercise performance is not necessarily the foremost factor influencing the quality of life in such subjects.…”

“…This is in accordance with the score below 70% found for many CFQ-R domains in our study (physical, social, body image, respiratory, vitality and treatment burden). Conversely, Donadio et al 21 assessed the pulmonary function and quality of life in a sample of children and adolescents with CF and found normal scores for most domains.…”

Bone mineral density is related to lung function outcomes in young people with cystic fibrosis—A retrospective study

“…This is the largest study exploring the effects of CF and disease severity on bone health outcomes in children with CF . In a large population of young Australian patients with CF, we found that the prevalence of severely low BMD ( z score less than −2) was 15.8%.…”