1996
DOI: 10.1056/nejm199610173351602
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Bone Mineral Density in Women with Depression

Abstract: Past or current depression in women is associated with decreased bone mineral density.

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Cited by 422 publications
(305 citation statements)
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“…To date, the evidence supporting an influence of depression on changes in BMD in postmenopausal women has not been uniformly strong. A few small cross-sectional and case-control studies reported an inverse association between clinically diagnosed depression and femoral or spinal BMD, 14,35,36 whereas a larger cross-sectional study found no association. 37 A recent 1-year longitudinal study of 320 postmenopausal white women (average age 56 years) did not observe an association between depressive symptoms and BMD loss at the more trabecular spine.…”
Section: Discussion Bmd Changementioning
confidence: 97%
See 1 more Smart Citation
“…To date, the evidence supporting an influence of depression on changes in BMD in postmenopausal women has not been uniformly strong. A few small cross-sectional and case-control studies reported an inverse association between clinically diagnosed depression and femoral or spinal BMD, 14,35,36 whereas a larger cross-sectional study found no association. 37 A recent 1-year longitudinal study of 320 postmenopausal white women (average age 56 years) did not observe an association between depressive symptoms and BMD loss at the more trabecular spine.…”
Section: Discussion Bmd Changementioning
confidence: 97%
“…14 They observed an association between clinically assessed depression and lower bone mineral density (BMD) and higher urinary cortisol excretion in premenopausal women. Prospective studies are limited.…”
Section: Introductionmentioning
confidence: 99%
“…In total, 21 articles complied with these criteria (Michelson et al. 1996; Amsterdam and Hooper 1998; Whooley et al. 1999, 2004; Robbins et al.…”
Section: Methodsmentioning
confidence: 99%
“…Dados da literatura indicam que a depressão está associada à menor densidade óssea 7,8 , sendo este um dos fatores de risco para a fratura de quadril, fornecendo, assim, fundamentação teórica para uma possível associação entre depressão e maior risco para a fratura. Desse modo, a depressão via aumento do cortisol 7 conduziria a desmineralização óssea e, consequentemente, maior risco para a fratura.…”
Section: Discussão E Conclusõesunclassified