Bone mineral density and risk factors of osteoporosis in children

Hanafy, Norhan M; Elsehaimy, Lofty A; Alzokm, Saad; El-Raheem, Sabah I. Abd

doi:10.1016/j.ejr.2022.01.003

Cited by 5 publications

(11 citation statements)

References 33 publications

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“…According to the WHO [7] , osteoporosis develops when the amount of bone resorbed exceeds the amount of newly generated bone, resulting in a net loss of bone mass.…”

Section: Introductionmentioning

confidence: 99%

“…Increasing awareness among pediatricians to identify risk factors and the clinical conditions or diseases that could lead to the development of osteoporosis made their screen for the possibility of asymptomatic osteoporosis in children with rheumatological disease [7] .…”

Section: Introductionmentioning

confidence: 99%

“…The most accurate way to quantify BMD in children is using dual-energy X-ray absorptiometry (DEXA) of the lumbar spine using the Z-score. As bone density fluctuates with age, Z-score rather than T-score, which is often utilized in adults, is employed in the pediatric population, and a Z score of -2 SD is considered osteoporosis [7] . Bone remodeling processes in terms of bone production and resorption can be detected using bone turnover markers [7] .…”

Section: Introductionmentioning

confidence: 99%

“…As bone density fluctuates with age, Z-score rather than T-score, which is often utilized in adults, is employed in the pediatric population, and a Z score of -2 SD is considered osteoporosis [7] . Bone remodeling processes in terms of bone production and resorption can be detected using bone turnover markers [7] . The aim of the current work was to determine the relationship between disease activity and BMD and bone turnover markers (serum osteocalcin for bone production and C terminal telopeptide of type 1 collagen (CTX) for bone resorption) in patients with juvenile idiopathic arthritis.…”

Section: Introductionmentioning

confidence: 99%

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Bone Mineral Density and Bone Markers in Juvenile Idiopathic Arthritis Patients

Soliman¹,

Labeeb²,

Zaiat³

et al. 2023

The Egyptian Journal of Hospital Medicine

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Introduction: One of the most prevalent adolescent chronic inflammatory illnesses, juvenile idiopathic arthritis (JIA), is linked to decreased bone mineral density (BMD) and an increased risk of osteopenia and osteoporosis, which raises the risk of fractures. Objective: The aim of the current work was to determine the relationship between disease activity and BMD and bone turnover markers (serum osteocalcin for bone production and C terminal telopeptide of type 1 collagen (CTX) for bone resorption) in patients with juvenile idiopathic arthritis. Materials and Methods: This study included 50 patients with JIA (female: male 20:30). These patients were diagnosed with JIA according to the criteria of classification of the International League of Associations for Rheumatology [ILAR]. BMD was measured by Dual-energy X-ray absorptiometry (DEXA) of the lumbar spine using the Z-score. The results were correlated with juvenile arthritis disease duration, disease activity, serum level of bone turnover markers, and serum level of vitamin D. Clinical disease activity was evaluated by juvenile arthritis disease activity score (JADAS-27). Results: There was a significant negative correlation between BMD (DEXA Z-score) and disease activity (P-value <0.001), bone turnover markers (P-value <0.001), and duration of JIA (P-value <0.05). There was a significant difference between vitamin D level and DEXA Z-score; DEXA Z-score was lower in vitamin D deficient patients. Conclusions: Patients with JIA who have a more active condition are more likely to develop osteopenia and osteoporosis. Osteoporosis incidence may be decreased, and bone health may be improved with timely and effective JIA treatment and disease activity control.

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“…According to the WHO [7] , osteoporosis develops when the amount of bone resorbed exceeds the amount of newly generated bone, resulting in a net loss of bone mass.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Bone Mineral Density and Bone Markers in Juvenile Idiopathic Arthritis Patients

Soliman¹,

Labeeb²,

Zaiat³

et al. 2023

The Egyptian Journal of Hospital Medicine

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“…Fatal injuries such as broken bones or body defects can occur due to thinning, brittle and porous bones, often called osteoporosis (Cherni et al, 2022). Some causes of osteoporosis are an unhealthy lifestyle (Anupama et al, 2020), suffering from anemia, and less consumption of nutritional foods (Hanafy et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Calcium Extract Characterization from Rajungan Crab Shell (Portunus pelagicus) and Bakau Crab Shell (Scylla serrata) using Calcination as Effervescent

Usman¹,

Permana²,

Ardinsyah³

et al. 2022

J. Akademika Kimia

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One of the prevention of osteoporosis is by taking calcium supplements. Crab shells are calcium sources that can be processed into supplements. Calcium extraction used the calcinations method at 900°C temperature for 4 hours. After calcining the crab shell powder, it was analyzed by using XRD and processed with the Highscore Plus application by using Rietveld method. The best calcium crystals will be used as raw material for effervescent powder. The results showed that calcium crystals from rajungan crab shells contained 0.4% CaCO3 with a crystallite size of 25.9001 nm and 99.6% CaO with a crystallite size of 82.7183 nm with a GoF value of 1.69979. Calcium crystals produced from bakau crab shells were 100% CaO with a crystallite size of 77.3397 nm with a GoF value of 1.90266. Calcium crystals from bakau crab shells were used as effervescent raw materials with 2 different formulations. The results of the organoleptic test from both effervescents showed the same results, namely in the form of a pale yellow powder with a orange scent and sour taste The results of the dispersion time test showed that the 2 formulations had met the requirements with the dispersion time of formula 1 being 31.67 seconds and formula 2 being 32.33 seconds. The results of the water content test of the two formulas met the requirements with the water content of formula 1 being 0.071% and formula 2 being 0.067%.

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The impact of chronic herpes virus infection on the bone system in children

Telesh,

Krutikova,

Sokolovskaya

2023

Det. infekc.

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Herpes virus infections currently are urgent problem in infectology, pediatrics and therapy. The feature of these diseases is the possibility of direct and indirect effects of the virus on various organs and systems: immune, nervous, endocrine, bone, in children in particular. The aim of the work is to summarize and systematize the available data on the impact of the chronic herpes virus infection on the bone system in children. Materials and methods: analysis of relevant Russian and international literature was carried out. Results: chronic herpes virus infections have pathological effects on bone system, in particular they can increase the risk of osteoporosis. Herpes viruses are involved in the pathogenesis of systemic inflammatory diseases, such as rheumatoid arthritis. Bone complications of herpes virus infections are the relevant issues. More research is needed to understand these complications more deeply.

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Bone mineral density and risk factors of osteoporosis in children

Cited by 5 publications

References 33 publications

Bone Mineral Density and Bone Markers in Juvenile Idiopathic Arthritis Patients

Bone Mineral Density and Bone Markers in Juvenile Idiopathic Arthritis Patients

Calcium Extract Characterization from Rajungan Crab Shell (Portunus pelagicus) and Bakau Crab Shell (Scylla serrata) using Calcination as Effervescent

The impact of chronic herpes virus infection on the bone system in children

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