Bone marrow involvement by lymphoproliferative disorders after renal transplantation: PTLD. Int. Survey

Izadi, Morteza; Fazel, Mozhgan; Saadat, Seyed Hassan; Taheri, Saeed

doi:10.4103/0973-1482.95176

Cited by 7 publications

(1 citation statement)

References 29 publications

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“…Patients with T‐cell PTLD, 123,124 CNS disease, 125 and advanced disease with bone marrow involvement 126 appear to have a poorer prognosis than other PTLD patients. PTLD confined to tonsillar/adenoidal tissue has been shown to be associated with a more favorable prognosis compared with other forms of PTLD 127 .…”

Section: Results/consensus Outcomesmentioning

confidence: 99%

The IPTA Nashville consensus conference on post‐transplant lymphoproliferative disorders after solid organ transplantation in children: IV‐consensus guidelines for the management of post‐transplant lymphoproliferative disorders in children and adolescents

Allen,

L'Huillier,

Bollard

et al. 2024

Pediatric Transplantation

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The International Pediatric Transplant Association convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post‐transplant lymphoproliferative disorders (PTLD) after pediatric solid organ transplantation. This report addresses the outcomes of deliberations by the PTLD Management Working Group. A strong recommendation was made for reduction in immunosuppression as the first step in management. Similarly, strong recommendations were made for the use of the anti‐CD20 monoclonal antibody (rituximab) as was the case for chemotherapy in selected scenarios. In some scenarios, there is uncoupling of the strength of the recommendations from the available evidence in situations where such evidence is lacking but collective clinical experiences drive decision‐making. Of note, there are no large, randomized phase III trials of any treatment for PTLD in the pediatric age group. Current gaps and future research priorities are highlighted.

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