Bone Marrow Examination

Bienzle, Dorothee

doi:10.1016/j.cveq.2019.11.002

Cited by 3 publications

(2 citation statements)

References 45 publications

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“…Bone marrow aspiration and biopsy is one of the beneficial tools for making the ultimate diagnosis of most of the hematological disorders (7). It is one of the invasive technique performed routinely in hematology (8). After this procedure bleeding, infection or any other complication are rarely reported (2).…”

Section: Discussionmentioning

confidence: 99%

Pattern of malignant hematological disorders using bone marrow aspirate and biopsy at tertiary care hospital, Karachi.

Mehwish Sajjad,

Shaheen Kouser,

Taha Khan

et al. 2022

j Muhammad Med Coll

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Introduction: Bone marrow aspirate and biopsy is an invasive method for identification, staging, and pursuing tumors. Current study designed to determine the frequency of malignant hematological disorders using bone marrow aspirate and biopsy at Dr. Ishrat ul Ebad Khan Institute of Blood Diseases (DIEKIBD).Objectives: To determine the frequencies of various hematological disorders usingbone marrow aspiration and trephine biopsy examinationMethodology: In this retrospective study, 333 patients presenting at DIEKIBD during January 2019 to December 2020 were included. All these patients underwentbone marrow examination and the reports were retrieved from the departmentrecords.Result: It was observed that about 80 (24%) of the bone marrow examinationswere done for staging in which 8 (2.4%) were not illustrated any primary diseasesinvolvement while 72 cases (21%) contained primary diseases. Among nonmalignant conditions, iron deficiency anemia, megaloblastic anemia and mixed deficiency anemia were the most frequent, while acute lymphoblastic leukemia, acutemyeloid leukemia and chronic myeloid leukemia were the most prevalent malignanthematological disorders.Conclusion: Pathological analysis of Bone Marrow via Aspirate and Trephine biopsy is a widespread approach in diagnosing, staging and prognosis of neoplastic aswell as non-neoplastic hematological disorders. Bone Marrow biopsy examinationanalysis has a significant value in the diagnosis and staging of malignant conditionsthan non-malignant disorder as in our study prevalence of malignant conditionswere more than non-malignant diseases. Key words: Bone Marrow Biopsy, Blood Disorder, Malignant Hematological Diseases.

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Section: Discussionmentioning

confidence: 99%

Pattern of malignant hematological disorders using bone marrow aspirate and biopsy at tertiary care hospital, Karachi.

Mehwish Sajjad,

Shaheen Kouser,

Taha Khan

et al. 2022

j Muhammad Med Coll

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“…The value of red bone marrow elements distinguishes of disease status from peripheral blood counts such as leukemia, congenital hematopoietic defect, and cytological responses for bone marrow (6,7). Most endemic diseases in Iraq such as anaplasmosis, babesiosis and theileriosis (8,9), and other disease states associated with anemia (10,11), may also be related to a defect in erythropoiesis and myelopoiesis (12,13), which can be characterized by a reduction in the levels of erythrocytes count, and of their other parameters in the blood periphery also dysplasia in one or more hematologic cell lines in the bone marrow (14,15). Authors assure that blood-borne diseases accompanied by diminished granulopoiesis and megakaryocytopoiesis in the bone marrow in the infected animal also the erythroid suppression, lymphocytic, monocytic, and macrophage hyperplasia are also found (3,16,17).…”

Section: Introductionmentioning

confidence: 99%

Routine red bone marrow smear in local breed claves at Basrah, Iraq

Al-Amery

2023

IJVS

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The state of the peripheral blood reflects on bone marrow activity. Therefore, we need to know the normal red bone marrow, and it can be a reference for those interested in hematology. Calves of apparently healthy local breeds were used to examine the state of the bone marrow, take a sample of peripheral blood before slaughter, and then a bone marrow biopsy that was immediately after slaughter. The calves that showed typical values for the parameters of red blood cells and total and differential white blood cells were included in the study. The result of bone marrow smears for nine normal calves appeared to have a faint coloration of granulated myelocytic than erythroid cells. As well as the myeloid was less than the erythroid, and that M: E ratio was 0.91±0.03. The erythroid series, Rubriblast, and Rubricyte were present as the most common progenitor red cell, including basophilic, polychromic, and normochromic cytoplasm, metarubricyte as a reduced nucleus. The myeloid series: Myeloblast, myelocyte was the most common progenitor white cells with granulation as basophilic, eosinophilic and neutrophilic within their cytoplasm, metamyelocyte with shrunken nuclei and band cell with horseshoe nucleus. They rarely found the megakaryocyte, enormous multinucleate cell.

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DXA parameters, Trabecular Bone Score (TBS) and Bone Mineral Density (BMD), in fracture risk prediction in endocrine-mediated secondary osteoporosis

et al. 2021

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Osteoporosis, a disease characterized by low bone mass and alterations of bone microarchitecture, leading to an increased risk for fragility fractures and, eventually, to fracture; is associated with an excess of mortality, a decrease in quality of life, and co-morbidities. Bone mineral density (BMD), measured by dual X-ray absorptiometry (DXA), has been the gold standard for the diagnosis of osteoporosis. Trabecular bone score (TBS), a textural analysis of the lumbar spine DXA images, is an index of bone microarchitecture. TBS has been robustly shown to predict fractures independently of BMD. In this review, while reporting also results on BMD, we mainly focus on the TBS role in the assessment of bone health in endocrine disorders known to be reflected in bone.

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Bone Marrow Examination

Cited by 3 publications

References 45 publications

Pattern of malignant hematological disorders using bone marrow aspirate and biopsy at tertiary care hospital, Karachi.

Pattern of malignant hematological disorders using bone marrow aspirate and biopsy at tertiary care hospital, Karachi.

Routine red bone marrow smear in local breed claves at Basrah, Iraq

DXA parameters, Trabecular Bone Score (TBS) and Bone Mineral Density (BMD), in fracture risk prediction in endocrine-mediated secondary osteoporosis

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